چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| حامد ابراهیم زاده لیل آبادلو | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Gastrointestinal Diseases، Blautia، Gut |
| خلاصه مقاله | Introduction: Blautia constitutes a significant proportion of the healthy gut microbiota. This article investigates the biological role of the genus Blautia in human health, with particular emphasis on its contribution to physiological homeostasis, its association with metabolic, digestive, and neurological disorders, and the probiotic potential of its constituent species. Materials and methods: A narrative review was performed through PubMed, Scopus, and Web of Science without time restrictions. Keywords included “Blautia spp.”, “gut microbiota”, and “gastrointestinal diseases”. Relevant studies were screened, and evidence was synthesized narratively to outline the role of Blautia spp. in gastrointestinal health and disease. Results: A reduced abundance of Blautia is associated with diseases such as obesity, type 2 diabetes, nonalcoholic fatty liver disease, irritable bowel syndrome, inflammatory bowel disease, gastrointestinal cancers, and neurological disorders such as Alzheimer’s and Parkinson’s. In addition, species such as B. producta and B. wexlerae have shown significant therapeutic effects in animal studies, particularly in reducing inflammation and improving metabolic disorders. Conclusion: As a key member of the gut microbiota, the genus Blautia plays a pivotal role in maintaining health and preventing disease. Current evidence supports its potential utility as a biomarker for disease diagnosis and as a promising candidate for probiotic development. Nonetheless, well-designed clinical studies are required to validate its therapeutic efficacy. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| certificate.pdf | 1404/10/16 | 131984 | دانلود |
| The Impact of Blautia.jpg | 1404/10/16 | 608174 | دانلود |
