چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| فاطمه جعفرلو | اول |
| ثمین شیبافر | دوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Multiple Sclerosis, Evoked Potentials; P300 |
| خلاصه مقاله | Background and aim:Multiple sclerosis (MS) is an inflammatory and demyelinating disease that can affect several areas of the central nervous system. In MS, appearance of sclerotic plaques in the auditory pathways can cause a significant loss of neural integrity. Given that conventional audiological assessments do not consider many changes that occur along the central auditory pathway; therefore, examining the auditory pathway, from the brainstem to the cerebral cortex, can help assess the integrity of this pathway in MS patients. Method and materials: We performed a literature review with the following keywords: multiple sclerosis, evoked potentials and P300. Five different databases (PubMed, Scopus, Web of science, Science Direct and Google Scholar) were independently screened. Publications in English were reviewed from 2000 to 2025. Results: In this review study,studiesshowed statistically significant differences between the MS patients and normal groups regarding the results of the auditory brainstem response and the latency of the Na and P300 waves.These differences were observed between the control and study groups for the latency of waves III and V and between the peaks I-III and I-V of auditory brainstem response and in the latency of P300, the values of which were higher for the group with MS. Conclusion: Patients with MS represent abnormalities in auditory evoked potentials, which indicate dysfunction of different areas of the central auditory nervous system in this disease. This suggests that the brainstem auditory pathway, in the regions from the cochlear nucleus to the lateral lemniscus, may be disrupted due to structural and/or functional changes in the transmission of the acoustic stimulus along the auditory pathway. So electrophysiological assessment of hearing (BAEP and P300) can contribute to the detection of changes in central auditory pathway in individuals with MS. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| poster 4 certificate.pdf | 1404/09/30 | 524460 | دانلود |
| congress booklet.pdf | 1404/09/30 | 1687713 | دانلود |
