چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| امیررضا ناصری | اول |
| بهنام گلابی | دوم |
| مهناز طالبی | سوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | INTRODUCTION and AIM Multiple sclerosis (MS) is a demyelinating inflammatory disease of the central nervous system, leading to a wide range of symptoms including cognitive dysfunction. Limited studies have investigated the relationship between cognitive impairment and plasma vitamin E level in MS patients. METHODS In this cross-sectional study, the questionnaires related to the demographic information were completed after obtaining the informed consent. Using the Cambridge Neuropsychological Test Automated Battery (CANTAB), patients’ cognitive function was assessed and specific domains of cognition were evaluated with SWM, RTI, RVP, and PAL subtests. Then the plasma level of vitamin E was evaluated. SPSS software version 27 was used for statistical evaluation. RESULTS Out of 82 studied patients, in 4 patients (4.9%) the level of vitamin E was less than 5 mcg/ml, and no significant difference was observed between the serum levels of vitamin E between patients with and without cognitive impairment (p-value: 0.52). The logistic regression showed that, age affects the cognitive function of patients, but the level of vitamin E had no effects on the cognitive function in MS patients. CONCLUSIONS There is no relationship between the cognitive function of patients and the serum level of vitamin E. |
| کلمات کلیدی | Vitamin E, multiple sclerosis, cognitive impairment |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| P102.pdf | 1404/09/27 | 214472 | دانلود |
| VitaminE.pdf | 1404/10/17 | 10816244 | دانلود |
