چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| شهرام صادق وند | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Severe brain disorders in which the epileptic electrical discharges during brain maturation may contribute to progressive psychomotor dysfunction -Common characteristics: -Related to early age -Aggressive EEG paroxysmal activity -Multiple and often drug-resistant seizure types -Cognitive, behavioral, and neurological deficits The most common epileptic syndrome in infancy -Charactenstics (one element may be missing): Epileptic (infantile) spasms: in all patients Hypsarrhythmia in EEG Arrest or regression of psychomotor development Onset 3-12 months (2 wks to 18 mo), peak at 5 mo -Incidence, 3-5 per 10,000 live births 1.3% of all epilepsies -Clusters of sudden, brief (0.2-2 sec), bilateral (symmetrical > asymmetrical) tonic contractions of the axial and limb muscles. Mixed > flexor (salaam spasms) > extensor -Slower than myoclonus and faster than tonic seizures -Eye deviation or nystagmoid movements occur in 60% and may be an isolated ictal symptom -Often followed by motionlessness (akinesia) and diminished responsiveness (arrest) for up to 90 sec -A cry or laughter often follows the end of the attacks Symptomatic (Genetic, structural-metabolic): 70%. Pre-, peri- and postnatal insuits, maiformations, neurocutaneous disorders (TS), Down syndrome. infections and rarely inborn errors of metabolism. Poor prognosis Probably symptomatic or Cryptogenic (Unknown) 25%. The main inclusion criteria is psychomotor deficits prior to development of seizures in infants with normal imaging and metabolic and other work-ups Idiopathic 5%. Normal pre-morbid development and possible hereditary predisposition (family history of seizures). May have a better prognosis |
| کلمات کلیدی | Epileptic , encephalopathy , infancy |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Epileptic Encephalopaty.pdf | 1404/09/05 | 1556930 | دانلود |
| Lecture.pdf | 1404/09/05 | 108589 | دانلود |
