چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| شیدا شعفی | اول |
| بهناز احمدی | دوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | key words: symptomatic seizures-diagnosis-treatment |
| خلاصه مقاله | Acute symptomatic seizures, diagnosis and treatment: A systematic review Sheida Shaafi.MD-Behnaz Ahmadi. MD Background: Following the International League Against Epilepsy (ILAE), ‘an acute symptomatic seizure is defined as a clinical seizure occurring at the time of a systemic insult or in close temporal association with a documented brain insult. An acute CNS insult, which may be metabolic, toxic, structural, infectious, or due to inflammation” The aim of this review is to provide information on the most important aspects related to acute symptomatic seizures(AsyS) challenges that will allow clinicians to accurately choice the best approach and management of acute symptomatic seizures and continue or discontinue them. In contrast to epilepsy, based on the general concept of AsyS, seizures are not expected to recur once the precipitating factor or condition has been removed or reversed. However, in practice, an increased risk for the development of epilepsy exists after AsyS caused by structural brain pathologies such as strokes. Awareness of the potential of certain CNS pathologies to cause AsyS is important to provide prompt treatment. Moreover, the accurate distinction between an AsyS and an unprovoked seizure provides a different prognosis and alters treatment. This review aims to provide review about the management and choice of drug in acute symptomatic seizures. Methods: Recent valued studies (2015-2025) were selected and reviewed. And diagnosis, approach and management of AsyS challenges were evaluated. Results: The high incidence of acute symptomatic seizures in the first year of life is associated with the relatively frequent occurrence of encephalopathies (e.g. hypoxic-ischemic encephalopathy), CNS infections, vascular etiologies and metabolic disorders in the neonatal period. Traumatic brain injuries, which occur predominantly in younger men, are the most common cause of acute symptomatic seizures in early adulthood. Alcohol and drug withdrawal is another common cause of acute symptomatic seizures that is more frequently seen in younger and middle-aged men. Cerebrovascular disease is the most common cause of acute symptomatic seizures in elderly patients. Acute symptomatic seizures, occurring shortly after a central nervous constitute nearly half of all seizure cases. However, there is a conspicuous absence of clear, comprehensive, and cohesive guidelines for the management of these seizures with anti-seizure medications, especially their duration of use. This lack of consensus on the optimal duration of therapy leads to prolonged treatments that may carry adverse consequences. It must be explored the risk of developing epilepsy for each specific etiology and identify the factors that influence this risk. Finally, to facilitate decision-making regarding treatment duration, and categorize acute seizures based on the temporal characteristics of hyper excitability as acute, subacute, and prolonged. Conclusion: It seems AsyS are among the most challengeable topics in seizure management and must be clarified most facts about diagnosis, approach and management of them. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| IMG_7094.jpeg | 1404/08/14 | 88001 | دانلود |
| symptomatic seizure drugs.docx | 1404/09/01 | 16567 | دانلود |
