| خلاصه مقاله | Harnessing advances in genomics and biomarker science, this approach tailors cancer prevention by identifying inherited and acquired risk factors, monitoring biological signals that precede disease, and guiding personalized lifestyle interventions. By combining genetic risk profiles with actionable biomarkers—such as circulating tumor DNA, epigenetic markers, and metabolic indicators—and aligning them with individual lifestyle factors like diet, activity, sleep, and exposure avoidance, we can stratify populations into more precise risk tiers. This enables targeted screening, early detection, and proactive behavioral modifications, while also informing chemoprevention and public health strategies. Ultimately, the integration of genetics, biomarkers, and lifestyle creates a dynamic, data-driven framework that emphasizes prevention, personalized risk communication, and sustainable lifestyle change to reduce cancer incidence and improve long-term outcomes. |