چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | امین خامنه |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | کمیته تحقیقات دانشجویی |
| کد مقاله | 88552 |
| عنوان فارسی مقاله | Identification the phenotypic and genotypic characteristics of biofilm formation in Escherichia coli isolated from urinary tract infections and their antibiotic resistance |
| عنوان لاتین مقاله | Identification the phenotypic and genotypic characteristics of biofilm formation in Escherichia coli isolated from urinary tract infections and their antibiotic resistance |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | چهارمین کنگره ملی و نخستین کنگره بینالمللی میکروبیولوژی کاربردی |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | اصفهان |
| سال انتشار/ ارائه شمسی | 1404 |
| سال انتشار/ارائه میلادی | 2025 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1404/02/24 الی 1404/02/25 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://amc2025.ui.ac.ir/fa |
| آدرس علمی (Affiliation) نویسنده متقاضی | Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| امین خامنه | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | phenotypic , Escherichia coli , genotypic, urinary tract infections |
| خلاصه مقاله | Background: Urinary tract infections (UTIs) are the most prevalent infectious diseases, and Escherichia coli is the most prevalent pathogen isolated from patients with UTIs. The products of sfa, afa and foc genes play a pivotal role in the binding of the bacterium to urinary tract epithelium Objective: Our aim was to investigate these genes in E. colis isolated from patients with UTIS. Context: This research was a cross-sectional study that was performed on urine samples of 150 patients with urinary tract infection who had been admitted at Amir Almomenin’s Hospital. The frequencies of the genes were determined using PCR. Biofilm formation and antibiotic resistance rates were determined using microtiter plate and disk diffusion methods, respectively. The P < 0.05 was considered statistically significant. The frequencies of sfa, afa and foc were 75.3%, 17.5% and 22.5%, respectively, indicating a significantly higher prevalence of the sfa gene. The most effective antibiotics against the E. coli were nitrofurantoin and amikacin. The highest microbial resistance rates were also observed against amoxicillin and ampicillin. Furthermore, the isolates demonstrated a capacity to form biofilms, with 12.7% exhibiting strong, 6.3% exhibiting moderate, 74.7% exhibiting weak, and 6.3% exhibiting no capacity to form biofilms. The expression of the sfa gene was found to be significantly associated with the formation of strong biofilms. Conclusion: Regarding the variability in the characteristics of E. coli strains associated with UTIs, it appears rational to adjust diagnostic and therapeutic methods according to the regional microbial characteristics. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Abstract.docx | 1404/07/07 | 364692 | دانلود |
| New Microsoft Word Document.docx | 1404/09/18 | 575286 | دانلود |
