چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| زینب محمدی | اول |
| مهین آهنگر اسکوئی | دوم |
| آرزو آزادی | سوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | |
| خلاصه مقاله | Prevalence of Adenovirus -Associated Gastroenteritis in Pediatric Patients in Northwest Iran. Background: Acute gastroenteritis (AGE) remains a significant cause of morbidity in children under five, with adenovirus being one of the important viral pathogens responsible for gastrointestinal infections. Adenoviruses are non-enveloped double-stranded DNA viruses that can cause a wide range of clinical manifestations, including respiratory, ocular, and gastrointestinal diseases. Among the various adenoviral stereotypes, types 40 and 41 are primarily associated with gastroenteritis, particularly in young children. Despite its global burden, data on the prevalence, seasonal distribution, and demographic characteristics of adenoviral gastroenteritis in specific regions remain limited. This study aimed to investigate the prevalence, seasonal patterns, and demographic associations of adenovirus-induced AGE in pediatric patients in northwest Iran. Methods: A cross-sectional study was conducted in 2023 on 180 children under five years old presenting with acute gastroenteritis (AGE) at a referral hospital. Stool samples were analyzed using Real-Time PCR (RT-PCR) to detect adenovirus. Data were evaluated for seasonal distribution and demographic associations of adenoviral gastroenteritis. Keywords: Adenovirus, Acute Gastroenteritis, Pediatric Infections, Epidemiology, Real-Time PC. Results: Adenovirus was detected in 7.8% of pediatric gastroenteritis cases. The infection was more prevalent among older children, particularly those aged 19 to 26 months. Although no statistically significant association was found between adenovirus prevalence and seasons, most cases were detected during autumn and winter, the colder months of the year. Additionally, no significant association was observed between gender and adenoviral infection rates. Conclusion: Adenovirus is an important viral cause of pediatric acute gastroenteritis (AGE) in northwest Iran, particularly affecting older infants and toddlers. While no significant seasonal variation was observed, most cases occurred during the colder months, highlighting the potential role of environmental and behavioral factors in transmission. These findings emphasize the need for continued epidemiological surveillance, improved diagnostic strategies, and further research on preventive measures to mitigate the burden of adenoviral gastroenteritis in young children. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| article.docx | 1404/05/18 | 165443 | دانلود |
| certificated.pdf | 1404/05/18 | 600366 | دانلود |
