چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| نسترن جوان | اول |
| رضا قوطاسلو | دوم |
| حسین صمدی کفیل | سوم |
| محمدیوسف رحیم پور | چهارم |
| جاوید صادقی | پنجم |
| حامد ابراهیم زاده لیل آبادلو | ششم |
| پردیس قوطاسلو | هشتم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | fecal microbiota transplantation, multi-drug resistant, Klebsiella pneumoniae, treat |
| خلاصه مقاله | • In order to treat multidrug-resistant (MDR) bacterial infections, the current choices are restricted(1) so it is one of the main challenges in medicine especially in immunocompromised patients and people who have excessive use of antibiotics(2). One the newest approach to combat this issue is Fecal microbiota transplantation (FMT) that is also used against Clostridium difficile infection(1). The aim of this study was search the treatments against MDR klebsiella pneumoniae by using FMT.• Materials & Methods • In order to answer this topic, our search was performed in google scholar from December 24, 2023 to December 29, 2023 and first of all to get the comprehensive results, keywords of fecal microbiota transplantation, multi-drug resistant, Klebsiella pneumoniae and treat were selected.• Results • There isn’t any both of extended spectrum β-lactamase(ESBL) and K. pneumoniae in urine and faeces after using FMT to treat patients that were suffering from urinary tract infections(3)also after using FMT, there isn’t any pathogen that some of them cause sepsis. It has been determined that Bacteroides and Firmicutes are the most abundant microbiota of donor by using 16S rRNA sequencing (2) and butyrate-producing anaerobic microorganisms like Faecalibacterium prausnitzii, Roseburia hominis, Coprococcus eutactus and Barnesiella spp by reducing the immune responses demonstrate the best results as super-donor(4). Klebsiella pneumoniae and Escherichia coli are the most microorganisms which are classified in carbapenem-resistant Enterobacterales that FMT is a useful tool to remove their infections(5).FMT is effective not only in eradicating ESBL and carbapenemase-producing Enterobacteriaceae infections, but also is against vancomycin-resistant Enterococci or methicillin-resistant Staphylococcus aureus infections(1).• Conclusion • In order to treat MDR klebsiella pneumoniae infections, FMT is one of the newest approach to combat this problem which type of the donor microbiota is so effective to get the best results but we must consider its safety especially in immunocompromised patients so, FMT needs more evaluations. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| fecal.pdf | 1404/04/22 | 237172 | دانلود |
| fecal.jpg | 1404/04/22 | 368111 | دانلود |
| participate.jpg | 1404/04/22 | 323743 | دانلود |
