| خلاصه مقاله | Background: Probiotics, particularly in fermented dairy products like yogurt, have gained significant attention for their potential health benefits. Among these, their role in modulating inflammatory markers and supporting gut health is of increasing interest. This systematic review aims to evaluate the effects of daily probiotic yogurt consumption on inflammatory biomarkers and gut health.
Methods: A comprehensive search was conducted across multiple databases including PubMed, Scopus, and Web of Science, to identify studies published between 2000 and 2024 that assessed the impact of daily probiotic yogurt intake on inflammatory markers (e.g., C-reactive protein, interleukin-6) and gut health indicators (e.g., microbiota composition, gut permeability). Studies included were randomized controlled trials, cohort studies, and clinical trials that provided relevant data on both outcomes.
Results: Out of 350 studies initially identified, 18 met the inclusion criteria. The pooled data suggest that daily probiotic yogurt intake significantly reduces systemic inflammatory markers, particularly C-reactive protein and interleukin-6, with moderate effects observed across both healthy and inflammatory conditions. Additionally, probiotic yogurt consumption was associated with improvements in gut microbiota diversity, increased beneficial bacteria (e.g., Lactobacillus, Bifidobacterium), and enhanced intestinal barrier function. Notably, these effects were more pronounced in individuals with pre-existing gut dysbiosis or inflammatory disorders.
Conclusion: Daily probiotic yogurt intake appears to exert a beneficial effect on both systemic inflammation and gut health. This review supports the potential of probiotic yogurt as a dietary intervention for reducing inflammation and improving gut microbiota composition. Future studies should focus on long-term clinical trials to further establish causality and explore the mechanisms underlying these effects. |
| کلمات کلیدی | Keywords: Probiotic yogurt, inflammation, gut health, systematic review, microbiota, C-reactive protein, interleukin-6, gut permeability. |