ارزیابی توزیع دوز در حجم هدف و اندام در معرض خطر (OARs) در رادیوتراپی سرطان های تحتانی مری با استفاده از سیستم برنامه ریزی درمان سه بعدی

Evaluation of Dose Distribution Within Target Volume and Organ at Risk (OARs) in Radiotherapy of Lower Esophagus Cancers Using a 3D Treatment Planning System


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نویسندگان: میکائیل ملازاده

عنوان کنگره / همایش: The 1st MEFOMP International Conference of Medical Physics , Iran (Islamic Republic) , شیراز , 2011

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نویسنده ثبت کننده مقاله میکائیل ملازاده
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده پزشکی
کد مقاله 87216
عنوان فارسی مقاله ارزیابی توزیع دوز در حجم هدف و اندام در معرض خطر (OARs) در رادیوتراپی سرطان های تحتانی مری با استفاده از سیستم برنامه ریزی درمان سه بعدی
عنوان لاتین مقاله Evaluation of Dose Distribution Within Target Volume and Organ at Risk (OARs) in Radiotherapy of Lower Esophagus Cancers Using a 3D Treatment Planning System
نوع ارائه پوستر
عنوان کنگره / همایش The 1st MEFOMP International Conference of Medical Physics
نوع کنگره / همایش بین المللی
کشور محل برگزاری کنگره/ همایش Iran (Islamic Republic)
شهر محل برگزاری کنگره/ همایش شیراز
سال انتشار/ ارائه شمسی 1390
سال انتشار/ارائه میلادی 2011
تاریخ شمسی شروع و خاتمه کنگره/همایش 1390/08/11 الی 1390/08/13
آدرس لینک مقاله/ همایش در شبکه اینترنت https://jbpe.sums.ac.ir/?_action=article&kw=90318&_kw=Conference
آدرس علمی (Affiliation) نویسنده متقاضی Medical Radiation Sciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

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میکائیل ملازادهدوم

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عنوان متن
خلاصه مقالهThe goal of radiotherapy is to maximize radiation dose to the tumor while keeping the dose to the surrounding normal tissues, especially organs at risk (OARs) below their respective tolerance doses. Thus, radiation dose distributions should be designed conforming to the entire lesion while sparing the normal tissues. Three-dimensional (3D) treatment planning systems have been demonstrated to improve tumor targeting and to reduce normal tissue volume exposed. The purpose of our study was to evaluation dose distributions within target volume and organs at risk (OARs) in 3D radiotherapy of abdominal and lower thoracic esophageal regions. A total of 17 patients (7 females and 10 males) of mean age 60.77±11.03 years were included in this study. All patients were examined with a 6-row spiral CT-scanner. After the acquisition of the CT, the images of CTs were transferred to a radiotherapy 3D treatment planning system (CorePLAN version 3.5) via DICOM format. Three 6 MV photon beams were designed and dose distribution analysis was edited to provide the best dose coverage to the planning target volume (PTV) while sparing OARs, especially spinal cord region using dose volume histograms (DVHs) of outlined structures. For all patients, the prescribed dose was 70 Gy at 2 Gy per fraction. Thus, the requirement Monitor units to deliver 200 cGy doses per fraction were calculated and dose of PTV and spinal cord as an OAR were evaluated. The gantry angles for each beam arrangement were 0o, 120o and 240o. The results showed that the mean and standard deviation of doses to PTV and spinal cord calculated from treatment planning system were (59.27±3.32) and (33.77±2.24) respectively. The three beam plans were acceptable as their doses to spinal cord were lower than the tolerable dose 45 Gy. This study confirms that 3D radiotherapy is more effective in decreasing dose to normal tissue without compromising dose distribution.
کلمات کلیدیradiotherapy

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Booklet.pdf1404/01/142077594دانلود
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