| نویسنده ثبت کننده مقاله | سارا سلاطین |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات علوم اعصاب |
| کد مقاله | 87156 |
| عنوان فارسی مقاله | Nanoparticle-Based Therapy Intervention for Stroke |
| عنوان لاتین مقاله | Nanoparticle-Based Therapy Intervention for Stroke |
| نوع ارائه | سخنرانی |
| عنوان کنگره / همایش | سیزدهمین کنگره علوم اعصاب پایه و بالینی |
| نوع کنگره / همایش | ملی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1403 |
| سال انتشار/ارائه میلادی | 2024 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1403/09/21 الی 1403/09/23 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://bcncongress.ir/Default.aspx |
| آدرس علمی (Affiliation) نویسنده متقاضی | Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| سارا سلاطین | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | The management of neurological diseases is very challenging due to the presence of the blood-brain barrier (BBB). The advancement of nanoparticle (NPs) provides a new direction for the management of neurological diseases. A wide variety of NP-based systems have been proved to be efficacious in passing the BBB after intranasal administration in vivo. However, physicochemical features of NPs (e.g. composition, shape, size, surface charge, and surface chemistry) exhibit significant effect on their biodistribution and ability to penetrate the BBB. The intravenous administration of natural NPs have received considerable interest in brain drug delivery because of their higher biocompatibility and lower toxicity. The surface modification of NPs with specific ligands has been highly suggested in recent years. However, it is necessary to address the differences in NPs permeability in healthy and disease animal models. Additionally, the development of potential in vivo imaging systems can help address whether and how NPs cross the BBB. |
| کلمات کلیدی | Nanoparticle, CNS, BBB, Stroke |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Certificate.pdf | 1404/01/04 | 364408 | دانلود |
| Program.pdf | 1404/01/04 | 323559 | دانلود |
| Invitation.pdf | 1404/01/04 | 286229 | دانلود |