چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | سمیه علی محمدی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات بیوتکنولوژی(زیست فناوری) |
| کد مقاله | 86964 |
| عنوان فارسی مقاله | اگزوزوم جعفری برای کاربرد در ترمیم زخم |
| عنوان لاتین مقاله | Parsley exosomes for wound healing application |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | یازدهمین کنگره بین المللی زخم و ترمیم بافت یارا |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | Tehran |
| سال انتشار/ ارائه شمسی | 1403 |
| سال انتشار/ارائه میلادی | 2024 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1403/08/30 الی 1403/09/02 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://www.wtrc.ir/fa/ |
| آدرس علمی (Affiliation) نویسنده متقاضی | Biotechnology Research Center, Tabriz university of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| سمیه علی محمدی | اول |
| لیلا روشنگر | سوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Exosomes are extracellular nanovesicles that resemble plasma membranes and are released by various cells to facilitate intercellular communication and modulate immune responses against pathogens. Their internal contents are safeguarded by a bilayer membrane. Plant-derived exosomes have distinct characteristics, and given the challenges and costs associated with extracting human exosomes—along with their potential to activate the immune system—plant exosomes may be a more advantageous alternative. This study is the first to extract and characterize exosomes from parsley, focusing on their morphological features and effects on healthy human fibroblast cells. The ultracentrifugation method was employed to isolate the exosomes, which were then prepared for dynamic light scattering (DLS) and scanning electron microscopy (SEM) analysis. The findings indicated that parsley exosomes are quite small, measuring approximately 70 nm, with a negative zeta potential. Subsequent tests, including the Bradford assay, were conducted to assess the presence of proteins within the exosomes, revealing a significant protein content. Additionally, polysaccharide compounds and freeze-drying techniques were utilized to stabilize the exosomes. Ultimately, the positive effects on fibroblast cell proliferation suggest that these exosomes hold great promise for wound healing applications. |
| کلمات کلیدی | Exosome, parsley, wound healing |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Exosomecerificate.pdf | 1403/12/06 | 760898 | دانلود |
| Abstract4.pdf | 1403/12/06 | 74522 | دانلود |
