چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| سید کاظم میری نژاد | اول |
| محمد حسین صومی | دوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background: The majority of rectal cancers (RC) originate from adenomatous polyps. At the time of diagnosis, patients with RC may present with adjacent non-cancerous polyps, or they may have no polyps at all. This study aims to compare the overall survival (OS) of rectal cancer patients with polyps to those without polyps at the time of diagnosis. Methods: We conducted a retrospective cohort study involving 593 patients diagnosed with rectal cancer between February 2007 and March 2017. Among these, 477 patients did not have associated polyps, while 116 patients had polyps at the time of diagnosis. Comparative survival analysis was performed using the Kaplan-Meier method, with statistical significance evaluated using the Breslow test. Results: Of the 593 rectal cancer cases, 116 (19.6%) were associated with polyps. The median follow-up period was 28 months. A significant difference in overall survival was observed between patients with and without polyps. The Kaplan-Meier analysis showed a 5-year OS rate of 36% for patients with polyps, compared to 51% for those without polyps (P < 0.05). Conclusion: Rectal cancer patients without associated polyps at the time of diagnosis have better overall survival compared to those with associated polyps. This finding suggests that the presence of polyps may be an adverse prognostic factor in rectal cancer survival. |
| کلمات کلیدی | Survival , Rectal cancer, Polyps |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| survival analysis of RC with and without associated polyps.pdf | 1403/11/13 | 593922 | دانلود |
| certificate-1.pdf | 1403/11/13 | 130117 | دانلود |
