چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| سید امین سیدرضایی | اول |
| معین کوهکلانی | دوم |
| جلیل راشدی | سوم |
| محمد اصغرزاده | چهارم |
| بهروز مهدوی پور صباحی | پنجم |
| وحید اصغرزاده | ششم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background and Aim: Digestive system disorders, such as irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD), and peptic ulcers, are common conditions that significantly affect patients’ quality of life. Emerging evidence suggests a potential link between the frequency of common colds and the exacerbation of these digestive disorders. The immune response triggered by recurrent colds may influence gastrointestinal health, potentially leading to or worsening existing digestive conditions. Additionally, using antibiotics to treat colds can disrupt the gut microbiota, further increasing the likelihood of developing digestive disorders by altering the balance of beneficial bacteria in the gut, leading to dysbiosis. This imbalance can compromise gut health and contribute to various digestive issues. Understanding these relationships is crucial for developing comprehensive treatment and prevention strategies. This study aims to evaluate the correlation between the frequency of colds and the risk of developing digestive system disorders. Methods: This study included 186 patients diagnosed with digestive system disorders referred for endoscopy at Imam Reza Hospital in Tabriz, and 185 healthy individuals who served as the control group. Ethical approval was obtained from the Ethics Committee of Tabriz University of Medical Sciences (IR.TBZMED.REC.1394.505). Both patients and controls completed a questionnaire that included a question about the frequency of colds. The control group comprised individuals without digestive system disorders, and they did not undergo endoscopy. Results: The study identified a statistically significant difference in the frequency of colds between the healthy control group and the GI patient group. Specifically, 76.4% of individuals in the healthy control group reported a low frequency of colds, compared to 55.4% in the GI patient group (P-value = 0.0001). For moderate cold frequency, the results were similar, with 22.7% of the healthy control group and 22.5% of the GI patient group reporting moderate cold frequency, though this correlation was not statistically significant (P-value = 1.00). Notably, only 2.7% of healthy individuals reported frequent colds, compared to 22.1% of GI patients (P-value = 0.0001). This study, which included 371 participants, demonstrated a strong association between a high frequency of colds and susceptibility to GI disorders. Conclusion: In conclusion, this study demonstrates a significant link between the frequency of colds and GI disorders. The findings show that GI patients have a higher cold history than healthy individuals. These results suggest that cold frequency could be a valuable indicator of GI health. Further research is essential to understand the underlying mechanisms and to develop effective preventive and therapeutic strategies for those at higher risk. |
| کلمات کلیدی | common cold, Digestive System Disorders, antibiotics, dysbiosis |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| ketabche.pdf | 1403/11/02 | 323354 | دانلود |
| 25_41_964e8238ee1556927c393a649bd5972d.jpg | 1403/10/16 | 352924 | دانلود |
