چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| هانیه کلاهی آذر | اول |
| نیما بهشتی زاده | دوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | The distribution and effectiveness of chemotherapeutic drugs, most importantly docetaxel, a mainstay of cancer therapy, have been transformed by the junction of nanotechnology and pharmacology. Docetaxel's therapeutic potential, previously limited by low solubility and significant adverse effects, has significantly improved with its incorporation into nanoplatforms such as nanofibers and nanoparticles. Through targeted distribution, controlled release, and enhanced bioavailability, this development significantly reduces systemic toxicity and enhances patient outcomes. With methods like electrospinning to customize drug release patterns, nanofibers provide a flexible framework for the controlled release of docetaxel. Nanoparticles, on the other hand, allow precise medication delivery to tumor cells through advanced encapsulating techniques such as nanoprecipitation and emulsion, reducing injury to healthy organs. By enabling focused treatment and cellular regeneration, these nanotechnologies not only enhance the pharmacokinetic characteristics of docetaxel but also offer new paths in regenerative medicine. This narrative review emphasizes the transforming effect of docetaxel-loaded nanoplatforms in oncology and beyond, highlighting the possibilities of nanotechnology to overcome the constraints of conventional chemotherapy and open the path for next developments in drug delivery and regenerative therapies. Through these developments, nanotechnology offers a new age of precision medicine, improving the effectiveness of cancer therapies and reducing side effects. |
| کلمات کلیدی | Cancer Therapy, Docetaxel-loaded nanoplatforms, Anticancer activity, Regenerative medicine |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Certificate Kolahi.jpg | 1403/10/09 | 1670773 | دانلود |
| Booklet 108.pdf | 1403/10/09 | 396452 | دانلود |
