| خلاصه مقاله | Introduction: The rise in global obesity rates has led to increased research on managing and preventing obesity. Nutraceutical and botanical dietary supplements are being explored for their potential to modulate body weight. Lemongrass (Cymbopogon citratus), commonly used in tropical countries and as a cooking ingredient, is being considered as a potential supplement for anti-obesity treatments. This meta-analysis aims to assess the impact of lemongrass on body weight.
Methods: Databases including PubMed, Web of Science, Scopus, Embase, and Google Scholar from 2003 to November 2024 using definitive keywords was searched. Only English articles focusing on animal studies were included. Human studies excluded due to limited numbers and study design heterogeneity. All relevant animal studies on rodents with changes in body weight as the primary outcome were included. The risk of bias and heterogeneity was assessed using the Cochrane Risk of Bias tool and I-square (I2) statistic, respectively. Out of 1010 articles that were evaluated, 5 studies met the criteria for inclusion.
Results: Findings showed that orally administering lemongrass led to a significant reduction in body weight (WMD = − 37.16 g (95% CI – 58.01, −16.30); P < 0.001).
Conclusions: Overall, most experimental research suggests that lemongrass can contribute positively to weight loss. This could be due to its capacity to stimulate energy expenditure, inhibit adipogenesis, modulate lipid metabolism, and inhibit digestive enzymes. Clinical trials can better clarify lemongrass's impact on obesity management. |