چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | ثمین حمیدی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | روانپزشکی و علوم رفتاری |
| کد مقاله | 86381 |
| عنوان فارسی مقاله | Personalized Treatment Optimization in Psychiatry: A Review of Therapeutic Drug Monitoring, Pharmacogenomics, and Biomarker Testing |
| عنوان لاتین مقاله | Personalized Treatment Optimization in Psychiatry: A Review of Therapeutic Drug Monitoring, Pharmacogenomics, and Biomarker Testing |
| نوع ارائه | سخنرانی |
| عنوان کنگره / همایش | هشتمین کنگره بین المللی زیست پزشکی (ICB 2024) |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | |
| سال انتشار/ارائه میلادی | 2024 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1403/08/19 الی 1403/08/26 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://www.icbcongress.com/2024/?lang=fa |
| آدرس علمی (Affiliation) نویسنده متقاضی | Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| ثمین حمیدی | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background: Psychiatric treatment outcomes remain highly variable, with many patients requiring multiple medication trials before achieving remission. Recent advances in precision medicine offer promising tools for treatment optimization. Aim: To systematically review and evaluate three key approaches in personalized psychiatric care: therapeutic drug monitoring (TDM), pharmacogenomic testing, and biomarker analysis. Methods: A comprehensive literature search was conducted across PubMed, Embase, and PsycINFO databases (2000-2024). Clinical trials, meta-analyses, and systematic reviews examining TDM, pharmacogenomics, or biomarkers in psychiatric treatment were analyzed. Results: Studies demonstrate that TDM improves treatment outcomes by optimizing drug concentrations, with 30-40% of patients requiring dose adjustments. Pharmacogenomic testing identifies relevant genetic variants in >90% of patients, leading to modified drug selection in 25% of cases. Emerging biomarkers show 70-80% accuracy in predicting treatment response. Conclusion: Integration of TDM, pharmacogenomics, and biomarker testing represents a promising strategy for psychiatric treatment optimization. Implementation challenges include cost considerations and standardization needs. Further research is needed to validate biomarker-based treatment algorithms. |
| کلمات کلیدی | precision psychiatry, therapeutic drug monitoring, pharmacogenomics, biomarkers, personalized medicine |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Biomedicine personalized.jpeg | 1403/10/05 | 1151210 | دانلود |
| Abstarct biomedicine personalized.docx | 1403/10/05 | 13010 | دانلود |
