چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| عزیزه رحمانی دل بخشایش | اول |
| مریم قهرمانی نسب | دوم |
| ثریا بابائی | سوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | The wound healing process is a complex biological process requiring therapeutic interventions to accelerate it. Due to their unique antibacterial and anti-inflammatory properties, zinc oxide nanoparticles have a high potential for promoting better wound healing. Due to these unique features, zinc oxide nanoparticles can control the infection of the wound site and, as a result, its effective regeneration, when they are integrated into the composition of biocompatible composites. This feature makes nanocomposites based on zinc nanoparticles a suitable alternative for traditional wound care methods [1]. In many chronic wounds, the wound-healing process is delayed or not done at all due to infections or metabolic disorders such as diabetes. Zinc oxide nanoparticles have emerged as a valuable solution to the challenges of wound healing due to their reaction with cellular processes and the ability to combat bacterial infections [2]. On the other hand, incorporating these nanoparticles with many biocompatible polymers such as collagen, gelatin, chitosan, and polyethylene glycol improves the physico-mechanical properties of wound dressings and strengthens their bioactive properties. To prepare Zinc Oxide NP-based composites, methods, such as electrospinning and chemical deposition, should be used that provide precise control over the dispersion of nanoparticles. The dispersion of nanoparticles in composites directly affects their performance. Zinc oxide nanoparticles prevent infection in the wound site by creating reactive oxygen species, and by accelerating the activity of fibroblasts and keratinocytes, they improve wound closure and tissue repair. Various studies have shown the efficiency of these structures in various wound-healing applications. It has been demonstrated that these materials enhance wound healing by reducing the risk of infection and accelerating the healing process. Additionally, they enhance collagen deposition, which is essential for tissue regeneration [3]. Among the various types of nanostructured composites, films and hydrogels based on zinc oxide nanoparticles are particularly effective in wound healing due to their sustained antibacterial function and the creation of a favorable healing environment. Also, in many studies, to increase the therapeutic output, in addition to zinc oxide nanoparticles, various restorative and bioactive agents such as growth factors are used [4]. In conclusion, significant advancements have been made in the field of wound care using Zinc Oxide NP-based composites. These nanostructured composites offer a multi-functional approach to treating severe and chronic wounds by combining the antibacterial benefits of zinc oxide nanoparticles with the structural and physical support of polymers |
| کلمات کلیدی | Wound Healing, Zinc Oxide Nanoparticles, Composites, Nanoengineering |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| certificate.JPG | 1403/10/03 | 116789 | دانلود |
| wtrc-00070094_2_240917143931 abstract.pdf | 1403/10/03 | 343555 | دانلود |
| Dr. Azizeh Rahmani Del Bakhshayesh.jpg | 1403/10/03 | 401113 | دانلود |
