چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| اسماعیل قره پاپاق | اول |
| سحر رضائی | دوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Fbrous dysplasia, Tc-99m MDP, bone scintigraphy |
| خلاصه مقاله | Aim/Introduction: Bone cells make an abnormal type of Äbrous bone when they are aÃected by Äbrous dysplasia caused by a gene mutation. Despite beginning to form before birth, abnormal bones are often not diagnosed until childhood, adolescence, or adulthood. As a result, this study aims to demonstrate the value of a whole-body bone scan when dealing with multiple skeletal involvement such as Paget’s disease and Äbrous dysplasia. Materials and Methods: A 22-year-old man presented for whole-body bone scintigraphy to assess skeletal pain and bone lesions with a history of left radius bone fractures 4 years ago and left femoral shaft fractures 2 years ago. In radiologic examination, osteolytic lesions were noted in the left femur of the patient who has been experiencing pain and numbness in his lower limbs since age 11. As a result of a biopsy performed in 2013, ABC (Aneurysmal Bone Cyst) was reported in the left lower limb. The patient complains of general body pain, especially in the ribs and pelvis, as well as movement limitation. Moreover, due to the pathological fracture of the left femur, a prosthesis has been placed there. Whole body bone scintigraphy was performed 3 hours after intravenous administration of 20 mCi 99mTcMDP using a Siemens dual-headed gamma camera with LEHR collimators. Results: As a result of the scan, a nuclear medicine specialist reported both irregular and diÃuse osteoblastic lesions in the skeletal system including the right maxilla and mandible, both sides ribs, the left hand and shoulder (with deformity), the left hemipelvis, the left lower limb (with mild deformity and proximal expansion) with high probability of Äbrous dysplasia. Following the bone scan result and sites of involvements, another bone biopsy was performed on the left femur and tibia, conÄrming Äbrous dysplasia. Conclusion: Therefore, the results indicate that a whole-body bone scan can be very useful in guiding and diagnosing rare and genetic bone conditions like Äbrous dysplasia that have multiple involvements, and it may delay the diagnosis process if it is not used. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| CR-Skeletal.pdf | 1403/09/21 | 82955 | دانلود |
| EPOST_EANM24_Dysplasia.pdf | 1403/09/21 | 1350041 | دانلود |
