| Background:
Etomidate, a short
-
acting hypnotic drug, plays a pivotal role in
induction for intubation, particularly in emergency settings. Its
favourable
hemodynamic profile renders it a suitable choice for patients with hemodynamic
instability
Methods:
In this system
atic review, we aim to delineate its role in emergency ward
settings. Through a systematic search across databases, we identified nine eligible
studies for inclusion. We searched the databases of PubMed, Scopus, ProQuest, and
Medline (Ovid) from 2004 to 20
23 for Randomized Controlled Trials (RCTs) and
observational studies in which the study population was referred to the emergency
department and received etomidate for Rapid sequence intubation (RSI)
.
Results:
These studies collectively underscored the safe
ty and efficacy of etomidate
in emergency patients, with its suppressive effects on the adrenal axis deemed
clinically insignificant
.
Conclusion
:
The rapid onset of action and favourable hemodynamic profile position
etomidate as a desirable agent for rapid
sequence induction. However, further studies
are warranted to strengthen recommendations in this regard
. |