چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | لیلا مقسومی نوروزآباد |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات طب تلفیقی |
| کد مقاله | 85831 |
| عنوان فارسی مقاله | A Review of the Role of Gut Microbiota in Obesity |
| عنوان لاتین مقاله | A Review of the Role of Gut Microbiota in Obesity |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | پنجمین همایش بین المللی تغذیه بالینی ایران |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1403 |
| سال انتشار/ارائه میلادی | 2024 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1403/07/25 الی 1403/07/27 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | www.icncongress.ir |
| آدرس علمی (Affiliation) نویسنده متقاضی | Research Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran. |
| نویسنده | نفر چندم مقاله |
|---|---|
| لیلا مقسومی نوروزآباد | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Gut Microbiota, obesity, short-chain fatty acids, inflammation, probiotic, prebiotic |
| خلاصه مقاله | A Review of the Role of Gut Microbiota in Obesity Abstract Introduction: This review article aims to discuss current findings on the role of gut microbiota in the pathogenesis of obesity. Methods: We explore the mechanisms by which gut microorganisms affect host metabolism. Furthermore, we discuss the impact of dietary patterns on microbial diversity and function and the potential of probiotics and prebiotics as therapeutic strategies for obesity management. Results: Numerous studies have identified significant differences in the gut microbiota profiles of obese individuals compared to lean individuals, with a higher prevalence of Firmicutes and a lower prevalence of Bacteroidetes. Specific gut bacteria are capable of breaking down complex carbohydrates into short-chain fatty acids, which can be absorbed and used for energy, contributing to increased fat storage. Gut microbiota can influence the secretion of hormones related to appetite regulation, such as increased levels of ghrelin and decreased levels of leptin, which can promote weight gain. Dysbiosis has been linked to systemic inflammation and metabolic disorders commonly associated with obesity, like insulin resistance. Diet significantly affects gut microbiota composition, with a high-fiber diet promoting microbial diversity and the growth of beneficial bacteria, while a high-fat, high-sugar diet tends to reduce diversity and promote obesity-related microbial profiles. Studies suggest that probiotic and prebiotic supplementation can lead to weight loss and improvement in metabolic markers, highlighting potential therapeutic strategies targeting gut health for obesity management. Conclusion: These results emphasize the critical role of gut microbiota in the development of obesity and underline the potential for microbiota-based interventions in obesity treatment and prevention strategies. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| ICN5poster (1).pdf | 1403/08/08 | 538741 | دانلود |
| LMN 1.docx | 1403/08/08 | 14878 | دانلود |
