چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| سپیده هزاری | اول |
| آزیتا دیلمقانی | سوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | The goal of this study is to investigate the sustained release of Centella Asiatica (CA) extract from the gelatin-based hydrogels reinforced with MIL-53(Fe) (Fe-MOF) for the potential use as wound dressing. To achieve antibacterial activity, the prepared polymer nanocomposite wound dressing hydrogel was loaded by CA extract. FESEM images represented a lot of interconnected pores within the network of the nanocomposite hydrogels leading to a higher water absorption capacity and drug encapsulation. The relase results showed that the prepared hydrogels show sustained release behavior. The antibacterial activity of prepared nanocomposite hydrogels was investigated by disc diffusion method revealing the significant inhibition zone growth for gram-positive and gram-negative bacteria. Cytotoxicity results showed that the prepared hydrogels are biocompatible. So, the prepared hydrogel are good candidate for potential wound dressing applications. |
| کلمات کلیدی | Keywords: Polymer nanocomposite, Sustained release; Antibacterial; Centella Asiatica; Wound dressing. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| congress.pdf | 1403/07/18 | 539889 | دانلود |
| format. hezari.docx | 1403/07/18 | 1471774 | دانلود |
