چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | سید امین سیدرضایی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پیراپزشکی |
| کد مقاله | 85607 |
| عنوان فارسی مقاله | Correlation Between Total Iron Binding Capacity (TIBC) and COVID-19 Severity |
| عنوان لاتین مقاله | Correlation Between Total Iron Binding Capacity (TIBC) and COVID-19 Severity |
| نوع ارائه | سخنرانی |
| عنوان کنگره / همایش | Covid Achievements & lesson learned Congress |
| نوع کنگره / همایش | ملی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | Tehran |
| سال انتشار/ ارائه شمسی | 1403 |
| سال انتشار/ارائه میلادی | 2024 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1403/07/05 الی 1403/07/06 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://cac2024.ir/index. |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Laboratory Sciences, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| سید امین سیدرضایی | اول |
| محمد اصغرزاده | دوم |
| جلیل راشدی | سوم |
| بهروز مهدوی پور صباحی | چهارم |
| وحید اصغرزاده | پنجم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background and Aim: The coronavirus disease-2019 (COVID-19) pandemic, driven by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus, has resulted in substantial global health challenges. Identifying factors that influence the severity of COVID-19 is essential for enhancing patient management and outcomes. Iron metabolism has emerged as a critical component in the pathophysiology of COVID-19. Total Iron Binding Capacity (TIBC) serves as a vital marker of iron status, indicating the capacity of transferrin to bind and transport iron. Variations in TIBC levels have been documented in numerous infectious and inflammatory diseases, including COVID-19. Despite these observations, the precise relationship between TIBC and COVID-19 severity remains inadequately explored. This study aims to elucidate the correlation between TIBC levels and the severity of COVID-19, thereby contributing to a deeper understanding of iron metabolism’s role in the progression of this disease. Methods: We reviewed 300 articles about COVID-19, TIBC, and their relationships from November 1, 2020, to December 30, 2023. Based on relevance and quality, we selected 55 articles for detailed analysis. Results: The findings demonstrate a consistent reduction in TIBC and serum transferrin levels among COVID-19 patients. This reduction is frequently linked to elevated oxidative stress, which can compromise cellular repair mechanisms and weaken immune responses. The findings also indicate that oxidative stress significantly contributes to the severity of COVID-19. Therefore, reduced levels of TIBC can increase the risk of severe COVID-19 in individuals. Furthermore, lower TIBC levels are often associated with poorer health outcomes and increased mortality rates in patients. Conclusion: The findings underscore the importance of monitoring TIBC levels as a potential marker for predicting severe outcomes in COVID-19 patients. Additionally, it is important to maintain appropriate TIBC levels as it could be crucial in enhancing patient prognosis, improving recovery rates, and significantly reducing mortality rates among affected individuals. |
| کلمات کلیدی | COVID-19, SARS-CoV-2, TIBC, Transferrin, Iron |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| TIBC_COVID19_Full_Sentences_Presentation.pdf | 1403/07/11 | 451396 | دانلود |
| certificate 3.jpg | 1403/07/11 | 331425 | دانلود |
| congress.jpg | 1403/07/15 | 2851025 | دانلود |
