چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| عزیزه فرشباف خلیلی | اول |
| مجید مبصری | دوم |
| ناهید تارویردی زاده | سوم |
| هانیه صالحی پورمهر | چهارم |
| ثریا بابائی | پنجم |
| عذرا بهروزی فرد مقدم | ششم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background and aim: The majority of patients with non-alcoholic fatty liver disease (NAFLD) are asymptomatic and are detected following incidental discovery of elevated ALT and AST. The gold standard to diagnose NAFLD is liver biopsy, but it is important to find non-invasive methods to diagnose patients. MRI imaging techniques today are strongly associated with histopathological findings. In this study, we intend to evaluate the severity of changes in fatty liver and the degree of inflammation of Liver and their relationship with ALT and AST changes in NAFLD elder patients. Material & Methods: In this analytical and descriptive study, 120 patients over 60 years old (60 men, 60 women) with average age of 68.61 ± 13.06, were evaluated. Patients were examined by MRI with in-phase (IP) and opposed-phase (OPP) sequences. Signal intensity, fatty liver index (FLI), and liver inflammation were calculated and the relation of these factors with levels of ALT and AST and AST/ALT ratio were assessed. Result:The most common cause of admission of elder patients were abdominal pain (66.7%), icterus (15%), high liver enzymes (13.3%), fever and general itching at the same person (1.7%). MRI findings were anormal in 88 patients (73.3%). There were significant analytical positive relations of X1 (p=0.03, r= 0.208) and X2 (p=0.02, r=0.212) with serum level of AST, and significant analytical negative relationship of SDR1 levels with ALT (p=0.04, r=0.186). Conclusion: According to the result of this study, there were no significant relationship of ALT with MRI findings based on fatty liver index (FLI) and liver inflammation. Therefore, serum level of ALT could not be a marker to diagnose or screening of NAFLD disease and it is not a good evaluation replacement for MRI. |
| کلمات کلیدی | Bone turnover marker, Bone mineral density, Postmenopausal woman |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Bone turnover.png | 1403/05/09 | 162195 | دانلود |
| Bone turnuver...png | 1403/05/09 | 204539 | دانلود |
| Booklet.pdf | 1403/05/09 | 9310511 | دانلود |
