چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| فریبا حیدری | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background and aim: Nowadays the longevity of the population and the increase in the prevalence of chronic diseases and their risk factors has emerged the risk of polypharmacy, especially in elders. Different definitions for polypharmacy are proposed, although the most agreed is the daily intake of five or more medicines for at least 90 days. Developing countries where most patients with chronic conditions and multimorbidity live, are at most risk of polypharmacy. However, this issue is less addressed in these regions. Various adverse health outcomes have also been indicated to be associated with polypharmacy, such as frailty, falls, drug-drug and disease–drug interactions, medical dosing errors, decreased quality of life and well-being of patients, lower adherence to medication, more hospitalization, and higher mortality. This systematic literature review aimed to investigate the prevalence of polypharmacy in the older above 65 years old population in Iran. Methods and Materials: We searched PubMed/MEDLINE, Scopus, Embase, and Google Scholar databases to identify relevant studies published from January 2000. Observational or cohort studies reporting the prevalence of polypharmacy in the older (+65 years) population were analyzed. Results: After a systematic literature review, we identified 386 articles. Of those, 23 studies fulfilled the inclusion criteria. The prevalence of polypharmacy ranged from 1.57% to 53.5 % among elderly people. Socioeconomic status was not associated with polypharmacy in 16 of the studies. The majority of studies showed that polypharmacy was higher among females and individuals with more than two chronic conditions. Seven studies reported a significant association between polypharmacy with urban living. The most commonly prescribed drugs were medications for the cardiovascular system, antiacids, anti-hyperlipidemic, blood glucose-lowering, nervous system, supplements, NSAIDs, and drugs used for musculoskeletal and joint diseases. Conclusion: This study from a developing country showed a high prevalence of polypharmacy in the older population. The prevalence of polypharmacy was very different based on the geographical region of the country, and the population studied. It seems critical to alert healthcare workers about the magnitude and side effects of polypharmacy in older people to prescribe necessary medications and prevent unnecessary prescriptions |
| کلمات کلیدی | Polypharmacy, Older, Drug, Medication |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| poly.pdf | 1403/04/04 | 53063 | دانلود |
| poly cert3.jpg | 1403/04/04 | 69628 | دانلود |
