چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | ندا دولت خواه |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | طب فیزیکی وتوانبخشی |
| کد مقاله | 84724 |
| عنوان فارسی مقاله | THE EFFECT OF PROBIOTIC SACCHAROMYCES BOULARDII SUPPLEMENTATION ON SOMECLINICAL AND PARA-CLINICAL FINDINGS OF PATIENTS WITH MULTIPLE SCLEROSIS |
| عنوان لاتین مقاله | THE EFFECT OF PROBIOTIC SACCHAROMYCES BOULARDII SUPPLEMENTATION ON SOMECLINICAL AND PARA-CLINICAL FINDINGS OF PATIENTS WITH MULTIPLE SCLEROSIS |
| نوع ارائه | سخنرانی |
| عنوان کنگره / همایش | چهارمین کنگره بین المللی و شانزدهمین کنگره تغذیه ایران |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1402 |
| سال انتشار/ارائه میلادی | 2024 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1402/12/02 الی 1402/12/04 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://inc2024.ir/MckUpload/file/INC_2024_Abstarct%20Book_compressed.pdf |
| آدرس علمی (Affiliation) نویسنده متقاضی | Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| ندا دولت خواه | اول |
| کیمیا مطلق | دوم |
| هرمز آیرملو | سوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Multiple Sclerosis (MS) is a chronic demyelination disease of the central nervous system (CNS). The gut‑brain axis involves communication between the nervous, endocrine, and immune systems. Probiotics can positively impact immune and inflammatory responses by regulating gut microbiota. A total of 40 MS patients (average age of 34.38 ± 6.65) were examined to determine the effect of the Saccharomyces boulardii supplement for four months compared to a placebo. The results showed that the Saccharomyces boulardii significantly decreased the inflammatory marker high‑sensitivity C‑reactive protein (hs‑CRP) compared to the placebo (P < 0.001). The serum antioxidant capacity (TAC) also increased significantly in the probiotic group compared to the placebo (p = 0.004). Both the probiotic and placebo groups showed a reduction in the oxidative stress indicator malondialdehyde (MDA), but there was no significant difference between the two groups. Pain intensity (measured by Visual Analogue Scale) and fatigue severity (measured by Fatigue Severity Scale) significantly decreased in the probiotic group compared to the placebo (p = 0.004 and p = 0.01, respectively). The probiotic group experienced significant improvement in some quality of life scales (measured by 36‑Item Short Form Survey) and somatic and social dysfunction subscale of General Health Questionnaire scores compared to the placebo group (p = 0.01). The study suggests that the Saccharomyces boulardii probiotic supplement may benefit inflammatory markers, oxidative stress indicators, pain, fatigue, and quality of life in MS patients. |
| کلمات کلیدی | Multiple Sclerosis; SACCHAROMYCES BOULARDII; inflammatory indexes; oxidative stress mental health; fatigue; pain; quality of life |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| The Effect of Probiotic Supplementation.pdf | 1403/02/29 | 959237 | دانلود |
| PrintCerPDf.pdf | 1403/02/29 | 589569 | دانلود |
| paper 4.pdf | 1403/02/31 | 1155346 | دانلود |
