| نویسنده | نفر چندم مقاله |
|---|---|
| نرجس صدیقی | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | gestational diabetes mellitus, HbA1c, ventricular hypertrophy |
| خلاصه مقاله | Objective Adequate management of blood sugar levels in pregnant women with gestational diabetes mellitus (GDM) can help prevent fetal cardiac complications. The objective of this study was to examine the correlation between maternal HbA1c levels in GDM and the occurrence of fetal left ventricular hypertrophy. Methods This cross-sectional study included women with GDM and gestational age 17-19 weeks. Key data points such as maternal age, insulin usage, gestational age, and fetal gender were carefully recorded Maternal HbA1c was measured in random blood samples with levels ≥6.5% regarded as abnormal. All participating underwent fetal echocardiography, during which measurements of left ventricular (LV) wall diameter were taken both during systole and diastole. Data were analyzed with SPSS software. Results Of the 90 mothers with a mean HbA1c of 5.79±0.99%, four (4.4%) had received insulin therapy. Of the 90 fetuses, three (3.3%) had abnormal LV wall diameter both during systole and diastole. Maternal HbA1c was significantly higher in fetuses with abnormal LV wall diameter than those with normal diameter (7.67±0.58% vs. 5.72±0.94%,P=0.002). Also, fetuses with abnormal LV wall diameter were from significantly older mothers (30.33±11.59 vs. 27.36±5.98 years,P=0.002). Moreover, all fetuses with abnormal LV wall diameter were from mothers with abnormal HbA1c (100% vs. 66.7%,P=0.010). Mothers’ insulin therapy and fetal gender were not different between fetuses with and without abnormal LV wall diameter (P=1.000). Conclusions Poor glycemic control of mothers with GDM together with their older age appear to be associated with fetal LV hypertrophy irrespective of maternal insulin therapy and fetal gender. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 1 (2).docx | 1403/02/17 | 16660 | دانلود |
| ticket_1066460402.pdf | 1403/02/17 | 147196 | دانلود |
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