چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| نرجس صدیقی | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background: one of the most prevalent birth disorders is Congenital heart defects (CHDs) worldwide. Research on humans has yielded inconsistent results about the effects of zinc on these groups. In children with CHD has been seen hyperparathyroidism and vitamin D deficiency; thus, this study aims to evaluate the serum vitamin D and zinc levels in children with CHD and compare them with a control group. Methods: This case-control study included children with CHD (N=53) admitted to Bandar Abbas Children’s Hospital from June 22 to December 21, 2018. The inclusion criteria of the study were the age between One-month-olds to 14 years, and echocardiography-confirmed CHD. A group of children without CHD were also evaluated as controls (n=53). After recording the demographic information of participants, 4cc blood samples were collected from children to measure vitamin D and zinc levels in the serum. Results: In the current study, there wasn't observed significant difference between groups in serum vitamin D levels (P=0.242). In contrast, the mean serum level of zinc was lower in CHD patients than in controls and the result was significantly differences and showed a medium effect (SMD=-0.67, 95% confidence interval [CI] -1.06; -0.28). On the other hand, both groups were comparable regarding the frequency of deficit and insufficiency of serum vitamin D (P=1.000 and P=0.767, respectively). However, the odds of zinc deficiency were 4.31 times greater in CHD children compared to the control group (OR=4.31, 95% CI 1.52; 13.31). Also, simultaneous insufficiency of zinc and vitamin D levels was only observed in CHD children (P=0.006). Conclusion: Zinc deficiency was observed in children with CHD in this study, while there was no difference regarding the deficit and insufficiency of the serum vitamin D or between CHD children and the control group. Future longitudinal studies are required to confirm these findings. |
| کلمات کلیدی | congenital heart disease, vitamin D, zinc |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| ticket_1066460402.pdf | 1403/02/17 | 147196 | دانلود |
| ticket_1066452647.pdf | 1403/02/17 | 147672 | دانلود |
| 1.pdf | 1403/06/25 | 546628 | دانلود |
| 2.pdf | 1403/06/25 | 334721 | دانلود |
