Relationship between Thyroid Hormone Levels in Euthyroid Patients before HSCT with Time to Achieve Neutrophil and Platelet Engraftment

Relationship between Thyroid Hormone Levels in Euthyroid Patients before HSCT with Time to Achieve Neutrophil and Platelet Engraftment


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نویسندگان: نسرین غلامی , سپیده تحسینی تکانتپه , بابک نجاتی

عنوان کنگره / همایش: اولین کنگره بین المللی و بیست و یکمین کنگره سراسری انجمن مدیکال انکولوژی و هماتولوژی ایران , Iran (Islamic Republic) , تبریز , 2022

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نویسنده ثبت کننده مقاله نسرین غلامی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات هماتولوژی و انکولوژی
کد مقاله 84205
عنوان فارسی مقاله Relationship between Thyroid Hormone Levels in Euthyroid Patients before HSCT with Time to Achieve Neutrophil and Platelet Engraftment
عنوان لاتین مقاله Relationship between Thyroid Hormone Levels in Euthyroid Patients before HSCT with Time to Achieve Neutrophil and Platelet Engraftment
نوع ارائه پوستر
عنوان کنگره / همایش اولین کنگره بین المللی و بیست و یکمین کنگره سراسری انجمن مدیکال انکولوژی و هماتولوژی ایران
نوع کنگره / همایش بین المللی
کشور محل برگزاری کنگره/ همایش Iran (Islamic Republic)
شهر محل برگزاری کنگره/ همایش تبریز
سال انتشار/ ارائه شمسی 1401
سال انتشار/ارائه میلادی 2022
تاریخ شمسی شروع و خاتمه کنگره/همایش 1401/08/27 الی 1401/07/29
آدرس لینک مقاله/ همایش در شبکه اینترنت
آدرس علمی (Affiliation) نویسنده متقاضی Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

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نویسنده نفر چندم مقاله
نسرین غلامیدوم
سپیده تحسینی تکانتپهاول
بابک نجاتیسوم

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عنوان متن
کلمات کلیدیEuthyroid patients ,HSCT ,Hormone Thyroid
خلاصه مقالهAbstract Patients Euthyroid in Levels Hormone Thyroid between Relationship :Engraftment Platelet and Neutrophil Achieve to Time with HSCT before Study Sectional-Cross Analytic An 1 Tekantapeh Tahsini Sepideh 1 Gholami Nasrin , 1 Nejati Babak ,* ,Sciences Medical of University Tabriz ,Center Research Oncology and Hematology 1. Iran ,Tabriz HSCT allogeneic of indication common most The :Introduction ,HSCT autologous of case the in and ,syndromes myelodysplastic include effective for target main The .leukemias and ,lymphomas ,myeloma multiple important most the is which ,HSCT after engraftment is hematopoiesis HSC which by process the is Engraftment .survival term-long for criterion hematopoietic all produce and proliferate to way their find BM the in cells day first the to equivalent is) NE (engraftment Neutrophil .cells subcellular 106 × 500 above reach counts neutrophil when days consecutive three of to equivalent considered is) PE (engraftment platelet and) 500> ANC (L / < reaches count platelet the when days consecutive three of day first the the in platelets received not has patient the that provided ,L / 109 × 20 onset-late most the of one usually is dysfunction Thyroid .days seven last thyroid of up-follow term-long therefore ,HSCT allogeneic of complications .recommended is tests function performed was study analytical sectional-cross This :Methods and Materials TFT between relationship the investigate to patients transplanted 37 on .PE and NE achieve to time the and HSCT allogeneic and autologous before They .HSCT before days three tests 4T and 3,T ,TSH normal had patients All was tissue thyroid’ patients the of examination and ,euthyroid clinically were 2.89, :mean with 0.32-5.45 was test TSH the of range normal The .normal 1.4 :mean with) 0.8-2 (1 4:T Free and 2.8, :mean with) 1.4-4.2 (1.98 3:T Free day first the after and ,daily checked was 1H-CBC ,HSCT After .ELISA on based 3 for L / 106 × 500 >remained count neutrophil the if ,L / 106 × 500> ANC of was PE and ,NE as considered was 500ANC of day first the ,days consecutive counts platelet the when days consecutive3 of day first the as considered .L / 109 × 20 > reach days 10>NE to time of probability the in observed was 6>OR An :Results the in also ,patients male and UNR the in 2.89>TSH with patients in 27 الی 29 مهر 1401 / ایران، تبریز 19 the in L/mU 2.89>TSH with patients in days 15>PE to time of probability of probability the in found was CI and value-p significant Statistically .UNR to time and) 0.036=value-P8.58,=OR (patients male in days 10>NE to time .(0.041=value-P14.32,=OR (UNR the in 2.89>TSH with patients in days 15>PE ,regression logistic multiple elimination-backward additional on Based (0.030 =value-P5.53,= OR (gender and) 0.354=value-P2.14,=OR(type disease of predictors best the were) 0.102=value-P0.20,=OR (3T and) 0.048=ueval-P10.70,=OR (level TSH while ,NE reaching of predictors best the were .PE reaching recommended cautiously be can levothyroxine dose Low :Conclusions euthyroid in HSCT performing before LNR the in 2.8 ≤to TSH achieve to discharge earlier cause ,PE and NE to times the reduce will which ,patients future possible of treatment prophylactic the be will as well as ,patients of comparing require will trials clinical Future .hypothyroidism induced-HSCT to treatment levothyroxine supplementary without and with subgroups two .therapy hormonal replacement this of approval or rejection Patients Euthyroid ,HSCT ,Hormone Thyroid :Ke

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book.pdf1402/12/207027930دانلود
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