| خلاصه مقاله | Abstract
Introduction: Bone tissue responds to various stimuli, such as physical activity (PA). However, changes in bone response to PA depend partly on the type and duration of PA. Bone turnover markers are dynamic indicators in which acute and short-term changes can predict subsequent changes in bone status.
Objectives: This study aimed to investigate the relationship between usual daily physical activity (UDPA) with bone markers (alkaline phosphatase, 25-hydroxy vitamin D3, calcium, and phosphorus), and demographic and reproductive characteristics in postmenopausal women.
Methods: This cross-sectional study was conducted on 500 postmenopausal women aged 50-65 years in Tabriz-Iran in 2018. The women were recruited by the simple random method. The IPAQ (International Physical Activity Questionnaire) was used to collect data to assess levels of PA. The laboratory tests of 25-Hydroxyvitamin D3, alkaline phosphatase, calcium, and phosphorus also used to examine bone function. Data were analyzed with SPSS/23 by Spearman correlation, Mann-Whitney, Kruskal-Wallis, and multiple linear regression tests.
Results: The variables of education (p = 0.036), income (p = 0.036), employment status (p = 0.009), sun exposure (p = 0.006), and history of exercise (p <0.001) were significantly correlated with PA. Among reproductive characteristics, only menopausal age showed a significant relationship (P = 0.048) with total PA levels. None of the anthropometric indices showed a statistically significant relationship with total PA. Serum calcium and phosphorus levels showed negative and inverse relationships with total PA. The intensity of this association was statistically significant only for the calcium (p = 0.023). 25-Hydroxyvitamin D3 and alkaline phosphatase variables were directly and positively but non-significantly correlated to the intensity of total PA.
Conclusion: UDPA with any levels has no effect on bone markers except for calcium. Despite of the beneficial effects of PA, our findings showed that UDPA without increasing total PA cannot affect bone health. For maximal effects of PA on bone health, it seems that a degree of intensity, continuity and regularity of PA programs should be considered to stimulate bone formation. |