چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| افسانه فرجامی | اول |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Biopharmaceuticals are a rapidly growing class of drugs that are derived from living organisms and are used to treat a wide range of diseases. In-vitro cell-based bioassays are an essential tool for evaluating the potency, efficacy, and safety of biopharmaceuticals during the drug discovery and development process. This manuscript provides a comprehensive review of the fundamental principles and methods of in-vitro cell-based bioassays for biopharmaceuticals, as well as the latest advances and applications in this field. We discuss the key factors that influence the design and performance of in-vitro bioassays, including the choice of cell type, the selection of relevant biological endpoints, and the optimization of assay conditions. We also highlight the challenges and opportunities in the development and validation of in-vitro bioassays for biopharmaceuticals, and provide examples of successful applications in drug discovery and development. Overall, this manuscript aims to provide a valuable resource for researchers and practitioners in the field of biopharmaceuticals and drug development who are interested in using in-vitro cell-based bioassays to accelerate and improve the drug discovery and development process. |
| کلمات کلیدی | Cell-based assay, Bioactivity, In-vitro bioassay, Potency Testing, Biopharmaceuticals, Peptides/Proteins. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| attendance 2jpg.jpg | 1402/10/27 | 1142744 | دانلود |
| cell based bioassay.jpg | 1402/10/27 | 1395828 | دانلود |
| bioassay (2).pdf | 1402/10/27 | 1200218 | دانلود |
