چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| ثمین حمیدی | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Biomarkers, Magnetic nanoparticles, Sample preparation, Clinical diagnostics |
| خلاصه مقاله | Measuring clinically relevant biomarkers is critical for disease screening, diagnosis, and therapeutic monitoring. However, analyzing trace biomarkers in complex biological fluids remains challenging. Magnetic solid phase extraction (MSPE) has recently emerged as a promising sample preparation approach owing to its simplicity, efficiency, and ability to selectively isolate biomarkers. Databases including PubMed, Web of Science, and Scopus were systematically searched for studies on MSPE for clinical biomarkers. Key findings on nanomaterial synthesis strategies, surface modifications, and applications in biomarker isolation were synthesized. Recent research demonstrates magnetic nanoparticles with tailored surface chemistry can selectively extract biomarkers like cancer antigens, neurotransmitters, and pharmaceuticals from matrices such as plasma, urine, and serum. MSPE enables clinically relevant limits of detection, high recovery, and purification in a rapid and simple workflow. This technique shows significant potential to improve clinical diagnostics. Further research on novel magnetic materials and surface functionalization is warranted. This review provides insights for researchers aiming to develop MSPE methods for sensitive and selective analysis of clinical biomarkers. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Manetic 2023.jpeg | 1402/10/20 | 2287950 | دانلود |
| Abstract magnetic.docx | 1402/10/20 | 15277 | دانلود |
