چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | هادی صادقزاده |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده علوم نوین پزشکی |
| کد مقاله | 83696 |
| عنوان فارسی مقاله | تهیه و ارزیابی داربست های نانوفایبری سه بعدی به وسیله الکتروریسی به کمک قالب |
| عنوان لاتین مقاله | Fabrication and Evaluation of 3D Nanofibrous Scaffolds Using Mold-assisted Electrospinning for Tissue Engineering |
| نوع ارائه | سخنرانی |
| عنوان کنگره / همایش | 10th International Congress of Wound and Tissue Repair |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1402 |
| سال انتشار/ارائه میلادی | 2023 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1402/09/08 الی 1402/09/10 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://wtrc.jdtums.ir/ |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Tissue Engineering, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| هادی صادقزاده | اول |
| احمد مهدی پور | دوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | 3D nanofibrous scaffolds, mold-assisted electrospinning, tissue engineering, regenerative medicine, osteogenic differentiation |
| خلاصه مقاله | Fabrication and Evaluation of 3D Nanofibrous Scaffolds Using Mold-assisted Electrospinning for Tissue Engineering Hadi Sadeghzadeh* Ahmad Mehdipour Department of Tissue Engineering, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran The main limitation of currently available electrospinning methods is the fabrication of three-dimensional (3D) nanofibrous scaffolds. Two-dimensional (2D)-fabricated nanofibrous scaffolds failed to recapitulate the in vivo 3D cellular microenvironment which is vital for the repair and regeneration of damaged tissues. In this study, we designed mold-assisted electrospinning as a new method for the fabrication of 3D nanofibrous scaffolds consisting of polycaprolactone (PCL) and type I collagen (Col I) with controllable and desirable shapes for future utilize in tissue engineering and regenerative medicine (TERM). For this purpose, we prepared a 3D mold of an aluminum sheet to build up the 3D nanofibrous scaffolds by electrospinning without using any pre/post-processing steps or instruments alongside this method. Next, we evaluated the physicochemical property, biocompatibility, and other requisites for employing fabricated 3D scaffolds in TERM. The results indicated that the prepared 3D nanofibrous scaffolds presented biocompatibility, high porosity, high surface-to-volume area, and good tensile strength. In addition, these 3D nanofibrous scaffolds can mimic the natural 3D cellular microenvironment and provide the mechanical and biochemical signaling for osteogenic differentiation of adipose-derived stem cells. Keywords: 3D nanofibrous scaffolds, mold-assisted electrospinning, tissue engineering, regenerative medicine, osteogenic differentiation |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 10th International Congress of Wound and Tissue Repair.pdf | 1402/10/16 | 299174 | دانلود |
| Abstract.pdf | 1402/10/16 | 96396 | دانلود |
| 10th International Congress of Wound and Tissue Repair.JPG | 1402/10/16 | 108962 | دانلود |
