چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| لیلا واحدی | اول |
| امیر واحدی | سوم |
| امین خامنه | چهارم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background: Angiomyxoid plexiform myofibroblastic tumor is a rare mesenchymal neoplasm that can occur in the stomach Patient introduction: A 38-year-old man presented with abdominal pain, mild anemia, and hyperbilirubinemia. CT scan and endoscopy revealed a solid mass (38*39 mm) in the gastric antrum without lymphadenopathy, suspicious for a gastrointestinal stromal tumor. Laparoscopy revealed a 4 cm gray submucosal mass in the stomach. Microscopic examination of the resection specimen showed proliferation of spindle cells arranged in a plexiform pattern within an abundant myxoid stroma in the submucosa. The spindle cells lacked atypia, mitoses, and necrosis. Histochemical stains was positive only for SMA. Finally, the patient was diagnosed with angiomyxoid plexiform myofibroblastic tumor. Discussion and conclusion: Angiomyxoid plexiform myofibroblastic tumor is an extremely rare gastric mesenchymal neoplasm with nonspecific symptoms like abdominal pain, weight loss, anemia and pyloric obstruction. Microscopically, these tumors demonstrate characteristic plexiform architecture and lack hypercellular areas, and Immunohistochemically, they are negative for S100, CD34, DOG1, and desmin, that distinguishing them from other mesenchymal gastric tumors. Therefore, plexiform myofibroblastic tumor in the differential diagnosis when evaluating gastric myxoid neoplasms, especially those with a plexiform pattern Should be considered. In addition, the diagnosis requires confirmation through immunohistochemical staining of tissue samples. |
| کلمات کلیدی | Plexiform Angiomyxoid Myofibroblastic Tumor, Gastrointestinal Stromal Tumor, Stomach |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Poster.pdf | 1402/09/27 | 591244 | دانلود |
| Certificate.jpg | 1402/09/27 | 81522 | دانلود |
