The management of lower urinary tract symptoms in multiple sclerosis; an umbrella review

The management of lower urinary tract symptoms in multiple sclerosis; an umbrella review


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نویسندگان: امیررضا ناصری , فاطمه طهماسبی , سکینه حاج ابراهیمی , مهناز طالبی , هانیه صالحی پورمهر

عنوان کنگره / همایش: Eighth MENACTRIMS Congress , United Arab Emirates , Abu Dhabi , 2023

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نویسنده ثبت کننده مقاله امیررضا ناصری
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه کمیته تحقیقات دانشجویی
کد مقاله 83469
عنوان فارسی مقاله The management of lower urinary tract symptoms in multiple sclerosis; an umbrella review
عنوان لاتین مقاله The management of lower urinary tract symptoms in multiple sclerosis; an umbrella review
نوع ارائه پوستر
عنوان کنگره / همایش Eighth MENACTRIMS Congress
نوع کنگره / همایش بین المللی
کشور محل برگزاری کنگره/ همایش United Arab Emirates
شهر محل برگزاری کنگره/ همایش Abu Dhabi
سال انتشار/ ارائه شمسی 1402
سال انتشار/ارائه میلادی 2023
تاریخ شمسی شروع و خاتمه کنگره/همایش 1402/09/17 الی 1402/09/18
آدرس لینک مقاله/ همایش در شبکه اینترنت https://www.sciencedirect.com/science/article/abs/pii/S2211034823008404
آدرس علمی (Affiliation) نویسنده متقاضی Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran

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نویسنده نفر چندم مقاله
امیررضا ناصریاول
فاطمه طهماسبیدوم
سکینه حاج ابراهیمیسوم
مهناز طالبیچهارم
هانیه صالحی پورمهرپنجم

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عنوان متن
کلمات کلیدیKeywords: multiple sclerosis; lower urinary tract symptoms; systematic review; umbrella review.
خلاصه مقالهPurpose: Lower urinary tract symptoms (LUTS) is prevalent among patients with multiple sclerosis (MS). This study aims to evaluate the efficacy and safety of different methods in MS-related LUTS. Methods: This study was conducted following the PRISMA statement. Systematic review studies which reported the efficacy and/or safety of a method for LUTS in MS are considered for inclusion in this study. A systematic search was conducted in PubMed, Scopus, Embase, Web of Science, and Cochrane databases with ('Multiple Sclerosis') AND (bladder OR urin*) AND ('systematic review') keywords in March 2023. The risk of bias is assessed using the Joanna Briggs Institute (JBI) critical appraisal checklist for systematic reviews. Results: Out of 348 results of database searches, 31 systematic reviews were included in this umbrella review. There is little evidence that reported appropriate efficacy and safety for alpha-blockers (indoramin, phenoxybenzamine, and tamsulosin), anticholinergics, desmopressin, intravesical vanilloids, mirabegron, stem cell therapies, neurotoxin treatments, cannabinoids, transcranial magnetic stimulation, and craniosacral therapy, and catheterization. In addition, peripheral nerve stimulations (sacral neuromodulation, spinal cord stimulation, tibial nerve stimulation) and pelvic floor muscle training are also found to be effective and safe in MS patients. Conclusion: Although, a high prevalence of LUTS in MS patients, there is a lack of well-designed randomized controlled trials (RCTs) regarding the management of MS-related LUTS, which makes evidence inconclusive. There is a need for future multi-center studies on this topic. Funding acknowledgments: The research protocol was approved and supported by the Student Research Committee, Tabriz University of Medical Sciences (grant number: 71911).

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