| خلاصه مقاله | Background: Currently, organ transplantation is one of the most effective treatment
options for patients with end-stage organ failure. The aim was to investigate
the relationship between patient attitudes toward the transplanted organ, organ
function, and adherence to medication regimens among organ transplant recipients.
Methods: This was a correlational study with a sample of 245 liver and kidney transplant recipients
recruited from medical centers and clinics in Tabriz, Iran. Data was collected via questionnaire
after obtaining informed consent from participants. Descriptive and inferential statistics were
used to analyze the questionnaire data. Frequency distributions and percentages were calculated
to summarize responses to each questionnaire item. Bar charts visually displayed general
data. Pearson’s parametric tests, chi-square, independent t-tests, and Spearman’s correlation
assessed relationships between research variables at the inferential level using SPSS version 21.
After presenting descriptive statistics, correlations between research variables were examined.
Results: The results showed that out of the three fields, including of )1. the recipient’s
concern about the transplanted organ, 2. Positive attitude towards the transplanted
organ, and 3. Psychological rejection and feeling of alienation of the transplanted
organ(, the highest score was related to the second field )27.40±5.31( and the lowest
score was related to the third field )14.68±3.54(. In terms of the mean Basel adherence
score, a score of 12.1±1.7 was obtained out of a possible score of 0-20, indicating high
adherence of patients to immunosuppressant medications. 155 participants )63.3%(
demonstrated complete adherence to immunosuppressive drugs, while the rest had
relatively high adherence. Additionally, results of the Spearman correlation test
showed a statistically significant positive correlation between each domain of the
questionnaire on feelings toward the transplanted organ, as well as the total score,
and the mean adherence to immunosuppressive medications score )p>0.01, r=0.25(
Conclusion: The results demonstrating a significant positive association between recipient attitudes
toward the transplanted organ and medication adherence highlight the importance of addressing
patient perceptions of their transplant. Careful attention to patients’ sentiments regarding
their graft may improve quality of life by optimizing immunosuppressive therapy compliance |