چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | مینا اسلامبولچیلار |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده داروسازی |
| کد مقاله | 82885 |
| عنوان فارسی مقاله | آیا دوز مکمل روزانه 1 میلیگرم اسید فولیک میتواند در بیماران سرپایی مبتلا به افسردگی از شدت بیماری بکاهد؟ |
| عنوان لاتین مقاله | Could one-milligram daily folic acid supplementation change the intensity of the disorder in outpatients with depression who use citalopram? |
| نوع ارائه | سخنرانی |
| عنوان کنگره / همایش | پنجمین کنگره بین المللی و بیست و ششمین کنگره فیزیولوژی و فارماکولوژی ایران |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | سمنان |
| سال انتشار/ ارائه شمسی | 1402 |
| سال انتشار/ارائه میلادی | 2023 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1402/07/19 الی 1402/07/21 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://koomeshjournal.semums.ac.ir/article-1-8065-fa.html |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مینا اسلامبولچیلار | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Folate, Depressive disorder, Citalopram, Supplement, Blood Folate Level |
| خلاصه مقاله | Introduction Low serum folate level was related to the higher prevalence of depressive disorders. This study aimed to assess the effect of folic acid 1mg/day on the intensity of depression symptoms. Methods This randomized-controlled clinical trial was registered to the Iranian Registry of Clinical Trials (IRCT20180115038373N1). The study was conducted at the Zanjan Haft-Tir Clinic, Zanjan, Iran. Twenty-four outpatients with major depression (a Beck Depression Inventory (BDI) score higher than 15 and a Hamilton depression rating scale (HDRS) score higher than 10 at enrolment) were randomly assigned to two groups. Both groups received citalopram (20mg/day) as their standard treatment. The intervention group received folic acid supplements (1mg/daily). The folate levels of serum, BDI, and HDRS scores were measured. The measurements were conducted before the intervention and in 45 and 90 days of follow-ups. Results The serum level of folate was increased for the intervention group. The HDRS and BDI Scores were reduced significantly in both groups after 90 days of follow-up. There were no significant differences between the two study groups in the reduction of depression scores. In the intervention group, the decrease in HDRS score was negatively correlated to the increase in serum folate level. Conclusion The use of 1mg/d folic acid was not significantly effective in the reduction of depression symptoms in patients with major depression |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| koomesh-v25n5p24-fa.pdf | 1403/01/21 | 264621 | دانلود |
| seman oral ppresentation.pdf | 1403/01/21 | 2298848 | دانلود |
