چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| ناهیده قره آغاجی | ششم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Natural bone is a nanocomposite that is made up of collagen protein fibers with apatite nanocrystals isolated in protein molecules. Therefore, the use of composites in the treatment of bone tissue regeneration is a suitable method of mimicking the extracellular matrix [1]. In this study, 8 adult New Zealand white male rabbits with radius bone surgery on both hands were studied in three control groups (group 1) including 5 radius specimens, nanocomposite (group 2). Nanocomposites were synthesized in the laboratory and FT_IR، XRD ، SEM/EDX ، MTT-assay evaluations were performed. Under general anesthesia and under specific conditions, a 10 mm long piece of radius diaphysis was cut and removed, then in group 2 nanocomposite were placed in the area and group 1 remained empty. Rabbits were clinically observed daily for 5 weeks. 35 days after surgery under general anesthesia, the area is examined macroscopically and the radius bone isolated in formalin is sent to the relevant laboratory for histopathological evaluation. Also, the day after surgery and 35 days after surgery, lateral and anterior-posterior radiographs were taken of the right and left anterior limbs from the radius and ulna. Radiographs were examined by a radiologist for the degree of ossification at the site of the defect and the healing process. It can be concluded that the ossification of polymer coated hydroxyapatite group is more than hydroxyapatite and control group and it is a suitable option for repairing bone defects in rabbits. |
| کلمات کلیدی | Polymer, Hydroxyapatite, Radius, Bone healing |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Histopathological and radiological investigation.png | 1402/07/25 | 279285 | دانلود |
| Certificate Histopathological and radiological investigation.jpg | 1402/07/25 | 117932 | دانلود |
