چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | سحر رضائی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پزشکی |
| کد مقاله | 82695 |
| عنوان فارسی مقاله | SPECT Imaging Predictors of Social Anxiety Disorder Treatment Response: A New Way Forward |
| عنوان لاتین مقاله | SPECT Imaging Predictors of Social Anxiety Disorder Treatment Response: A New Way Forward |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | 36th Annual Congress of the European Association of Nuclear Medicine |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Austria |
| شهر محل برگزاری کنگره/ همایش | وین |
| سال انتشار/ ارائه شمسی | 1402 |
| سال انتشار/ارائه میلادی | 2023 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1402/06/18 الی 1402/06/22 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://eanm23.eanm.org/ |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Nuclear Medicine, Medical School, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| سحر رضائی | اول |
| اسماعیل قره پاپاق | دوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Aim/Introduction: Precision psychiatry aims is to accurately predict treatment response. Here, we tested pre-treatment patient characteristics and functional imaging markers to predict treatment response accuracy in patients with social anxiety disorders (SAD). Materials and Methods: The selective serotonin reuptake inhibitor (SSRI) escitalopram or placebo was administered for 9 weeks to 40 SAD patients (mean SD age 32.1 ± 8.2 years, 20 women). The Clinical Global Impression Improvement scale was used to define treatment responders (CGI-I ≤ 2). Imaging with single photon emission computed tomography (SPECT) was conducted before and after treatment. Based on pre-treatment neuroimages, support vector machines (SVMs) were used to separate responders from non-responders. SVM models were tested using leave-one-subject-out cross-validation. Results: High accuracy was achieved by classifying treatment responders from non-responders using a linear SVM. Higher post-treatment perfusion was observed in responders compared to non-responders, particularly in those treated with SSRIs. Conclusion: Based on these results, psychiatric symptoms of clinical recovery are consistent with functional brain perfusion imaging findings on an individual basis. |
| کلمات کلیدی | Keywords: SPECT, Social phobia, SSRI, SVM |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| EPOST_EANM23_SRezaei_Brain.pdf | 1402/07/11 | 380814 | دانلود |
| Brain.pdf | 1402/07/11 | 86724 | دانلود |
