چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | افشین قلعه گلاب بهبهانی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات سلامت کودکان |
| کد مقاله | 82527 |
| عنوان فارسی مقاله | مسمومیت کلیوی داروهای گیاهی در کودکان |
| عنوان لاتین مقاله | Renal Toxicity of Herbal Medications in Children |
| نوع ارائه | سخنرانی |
| عنوان کنگره / همایش | یازدهمین کنگره تازه های کودکان و نوزادان |
| نوع کنگره / همایش | ملی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | تبریز |
| سال انتشار/ ارائه شمسی | 1402 |
| سال انتشار/ارائه میلادی | 2023 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1402/05/25 الی 1402/05/27 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://rada.tbzmed.ac.ir/News/16381/ |
| آدرس علمی (Affiliation) نویسنده متقاضی | Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, IRAN |
| نویسنده | نفر چندم مقاله |
|---|---|
| افشین قلعه گلاب بهبهانی | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Botanicals, Herbal Medication, Children, Renal Toxicity |
| خلاصه مقاله | Background Use of botanicals as dietary supplements and herbal medications is increasing. Many people falsely believe that “natural” products are harmless; therefore, they readily trust on herbal medicine. Most herbal medications induce their renal toxicity by aristolochic acid, which causes aristolochic acid nephropathy. Discussion Different types of traditional herbal medicine are used for treatment of various diseases in approximately 80% of population from different countries. It is not easy to assess all toxic effects of herbal products because of their ever-changing chemical composition based on different factors such as growing environment, seasonal cycle and extraction techniques. Therefore, no one can find a single product of a given plant that identically represents all samples of the same plant worldwide. Besides, ingestion of a single herbal medication can result in different outcomes, because pharmacokinetic modeling of botanicals including their absorption, distribution, metabolism, and excretion differ widely among different individuals. Up to now, as the toxicology of different herbal medication in children is not fully known and their antidotes are not introduced yet, botanical toxicity is very challenging. Moreover, Traditional herbal medications can induce nephrotoxicity by a wide variety of mechanisms, including diminishing renal blood flow, damaging compartments through the nephron, and urinary obstruction. Pathological changes accompanying renal toxicity caused by herbal medications may include: Fanconi syndrome with tubular atrophy, significant renal interstitial fibrosis, swelling of endothelial cells with thickening of afferent and interlobular arterioles, and even urothelial carcinoma. Conclusion There is increasing case reports of pediatric renal toxicity associated with using herbal products, so it is not safe to recommend herbal medications to children. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Dr.Behbahan Article Abstract.docx | 1402/06/25 | 15511 | دانلود |
| Congress Poster.jpg | 1402/06/25 | 58750 | دانلود |
| ircme.ir_Author Certificate.pdf | 1402/06/25 | 87369 | دانلود |
