چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهدی اصغری عظمی | اول |
| مهین آهنگر اسکوئی | دوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Introduction Alzheimer's disease (AD) is a neurological condition that progresses over time and has a high incidence of morbidity, impairment, and mortality, adding considerably to the burden of public health across the world. The failure of drug development over the past few decades has highlighted the necessity and value of looking at new therapeutic agents, such as probiotics, which are live microorganisms that, when given to a host in sufficient quantities, improve their health, that can be used to overcome various diseases, especially neurological abnormalities. Materials & Methods : For this study, the keywords ' Alzheimer ',' neurological disorders', and ' Probiotic', in the databases PubMed, Google Scholar, Sid, and MagIran between 2020 and 2023 were searched and 14 articles were chosen, studied and analyzed. Results: As an alternative, an unhealthy microbiome damages the gut epithelial barrier by causing persistent gastric inflammation, which leads to neuroinflammation and quickens the onset of AD. When taken as a stand-alone supplement, probiotics have shown significant promise in slowing the progression of Alzheimer's disease. They achieve this effect through a variety of mechanisms, most notably by maintaining intestinal microbial balance, enhancing food absorption, and fortifying the immune system. Conclusion: Probiotic use for AD has not been associated with any negative side effects. In order to identify AD-specific alterations in the gut microbiome that may provide new information about probiotics as an excellent therapeutic target in the future, further clinical studies must be carried out. |
| کلمات کلیدی | Alzheimer, microbiome, neurological disorders, probiotic |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| probiotic.pdf | 1402/06/19 | 225926 | دانلود |
| probioticgovahi.pdf | 1402/06/19 | 176583 | دانلود |
