| خلاصه مقاله | Abstract:
Background: There is no clear evidence that pharmacological interventions can improve women’s satisfaction with the birth experience.
Methods: We searched databases in English (MEDLINE, Cochrane Library, Embase, ProQuest, Scopus and Web of Science) and Persian (SID and Magiran) from inception until 2018, for clinical trials that pharmacological pain relief methods were compared with routine cares or non-pharmacological methods. The evaluation of studies in terms of risk of bias was conducted using the Cochrane Handbook. Meta-analysis results were reported as OR and 95% confidence interval. In meta-analysis, subgroup analysis was performed based on the type of intervention. Due to the heterogeneity of over 30%, a random effect was reported instead of the fixed effect. The heterogeneity was evaluated using I 2, T 2 and Chi 2. The evaluation of the quality of the studies was also examined using the GRADE approach.
Results: The results of 7 studies with low-quality in meta-analysis, showed that pharmacological
methods significantly improved satisfaction with birth experience (OR = 2.99; 95% CI: 1.37 to
6.52; P = 0.006). However, meta-analysis of subgroups showed that only inhalation of Entonox gas (OR = 6.51; 95% CI: 3.47 to 12.22; P < 0.001), in contrast to epidural analgesia (OR = 1.19; 95% CI: 0.62 to 2.27; P = 0.60) and Hyoscine injection (OR = 2.58; 95% CI: 0.93 to 7.20; P = 0.07) significantly improved satisfaction with birth experience.
Conclusion: Pharmacological interventions such as epidural may not provide women with satisfaction with birth. |