چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| رها مرکزی موقر | دوم |
| فریبا اسلامیان | دوم |
| علیرضا پیش گاهی | سوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background and Aim: Platelet-rich derivatives are being increasingly used in the treatment of tendon-related pathologies as a rich source of growth factors which aims at providing a regenerative stimulus in the tendon. We sought to ascertain if local application of platelet lysate(PL) to augment rotator cuff repair improves outcomes compared to ketorolac tromethamine treated group. Methods: A total of 40 patients,18 to 70 years,with diagnosis of RCT and symptoms for ≥3 months were randomized to receive sub-acromial injections of PL (2 ml) every week for a total of 3 injections and two injection of ketorolac tromethamine (30 mg) every two weeks in addition to a training program.PL from all participants was prepared following standard protocols.Patients were randomized into a PL group (n=20) and ketorolac (control group,n=20).Visual Analogue Scale (VAS), Shoulder Pain and Disability Index (SPADI) and shoulder range of motion (ROM) were assessed at baseline and at 1 and 6 months after injection. Results: 40 patients completed 6 months follow-up. Within each group, SPADI and VAS scores showed significant improvements compared with baseline at all-time points (P<0001). In the range of motion measures, no significant difference after ketorolac therapy was noted. The outcomes were identical at the initial and short-term state in both control and PL groups; whereas,when considering the 6-month period, there is a seemingly remarkable superiority in PL group in all parameters Conclusion: This study suggests that local injection of PL led to favorable clinical outcomes for the RCT treatment after 6 months and supports that PL probably has the capability of improving the symptoms and bringing back the functionality in capacities. Hence,these consequences can open doors for PL a new horizon as well as a second choice for RCT treatment in the future. |
| کلمات کلیدی | Platelet lysate,Tendon healing,Rotator cuff tendinopathy |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| lysiat platelet abstract.pdf | 1402/04/09 | 169291 | دانلود |
| Certificate.aspx.pdf | 1402/04/09 | 257682 | دانلود |
