چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| فریبا اسلامیان | اول |
| نگار تلسچیان تبریزی | دوم |
| شیوا یوسف زاده | سوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background and Aim: Systemic Lupus Erythematosus (SLE) is an autoimmune inflammatory disease, which produces antibodies against various components of the cell. The aim of this study was to investigate the incidence of myositis and neuropathy concomitant with lupus among patients with SLE referred to the Electrodiagnosis Center of Physical Medicine and Rehabilitation clinic of Imam Reza Hospital in Tabriz. Methods: Patients with SLE who have been admitted in the rheumatology inpatient service and complained of hands or feet numbness, paresthesia or weakness were referred to electrodignosis center of rehabilitation clinic for performing NCS/EMG during the 3- year period. The incidence of neuroapthies and myoapthies among lupus patients, their electrodiagnostic pattern, involved muscles, severity of disorder, the occurrence of each kind of the neuroapthies and myopathies and its relationship with age, sex and duration of the disease were determined. Results: Out of total 127 SLE patients, 45 cases were referred for electrodiagnosis and among them 32 patients had abnormal and 13 patients had normal EDX. 87.5% of patients were female and 12.5% were male. The mean age was 40.45 ± 14.13 years old. 28(22%) patients had myopathy, including 10(35.71%) cases of inactive dispersed myositis, 8 (28.57%) cases of polymyositis, 6(21.42%) cases of corticosteroid myopathy and 4 (14%) cases of active patchy myositis. Of the 17 (13% of total) neuropathic cases, the highest percentage of neuropathy was related to sural or median mononuropathy with a frequency of 8 (47.04%), sensorimotor polyneuropathy in 5 (29%) and mononeuritis multiplex in 4 (23%) of cases, respectively. The study also looked at fibrillation in different types of myopathies, in which active dispersed myositis and polymyositis both produced the most fibrillations and steroid induced myopathy caused the least fibrillation. No significant association was found between electrodegnostic findings severity and age or sex. However, significant correlation was noted between incidence of polyneuropathy and age. Conclusion: Neuropathy and myopathy are among common neuromuscular complications of SLE.Of total of 127 hospitalized patients, 22% revealed the myopathy and 13% neuropathy. Among myopathies, 50% was belonged to patchy myositis, 28% polymyositis and 22% steroid myopathy. Sural or median Sensory mono neuropathy is the most common form of neuropathy. |
| کلمات کلیدی | poly myositis, poly neuropathy, systemic lupus erythmatosis, CTS, electrodiagnosis |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| lupus article abstract.pdf | 1402/04/06 | 206873 | دانلود |
| lecture certificate.pdf | 1402/04/06 | 241529 | دانلود |
