چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | مهرناز مطیعی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده دندانپزشکی |
| کد مقاله | 81120 |
| عنوان فارسی مقاله | Diagnostic salivary biomarkers in oral cancer: A review |
| عنوان لاتین مقاله | Diagnostic salivary biomarkers in oral cancer: A review |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | 1st International Congress of Biomarkers |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | ارومیه |
| سال انتشار/ ارائه شمسی | 1401 |
| سال انتشار/ارائه میلادی | 2023 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1401/12/03 الی 1401/12/05 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://icb.umsu.ac.ir/ |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of prosthodontics, faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهرناز مطیعی | اول |
| کتایون کاتبی | دوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Oral cancer, Oral potentially malignant disorders, Salivary biomarkers |
| خلاصه مقاله | Background: Oral cancer is usually diagnosed at advanced clinical stages due to its asymptomatic nature and absence of symptoms in early phases. One of the major causes of failure in oral cancer treatment and its poor prognosis is delayed diagnosis. Salivary cytokines are noninvasive diagnostic tools, which have been studied as potential diagnostic biomarkers for early diagnosis of oral cancer and oral potentially malignant disorders. Materials and Methods: Electronic literature search was conducted in Scopus, Medline, Embase and Web of Science databases using the terms “oral cancer”, “oral leukoplakia”, “oral potentially malignant disorders”, “saliva”, “cytokine”, and “interleukin” until January 2022. The articles were screened by two independent reviewers and data were extracted. Results: A total of 233 articles were screened and 37 articles were included in the study. Interleukin (IL) 1β, IL6, and IL8 were significantly higher among patients with oral cancer compared to healthy controls. Patients with oral potentially malignant disorders, in comparison with healthy controls, showed significantly higher salivary levels of IL-6 and TNF-α. Conclusions: It seems some salivary cytokines increase in patients with oral cancer and oral potentially malignant disorders. Therefore, using salivary biomarkers along with other techniques could be used as a screening tool to improve the early detection of these conditions. More clinical studies are needed to reach a standard range for salivary biomarkers. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| icb-1052.pdf | 1401/12/15 | 1439736 | دانلود |
| icb-1052___57049.docx | 1401/12/15 | 20322 | دانلود |
| icb-1052___Jy48R.jpg | 1401/12/15 | 1425911 | دانلود |
