چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | سید کاظم میری نژاد |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | بیماری های گوارش و کبد |
| کد مقاله | 80848 |
| عنوان فارسی مقاله | تأثیر سطوح هموگلوبین در بقای سرطان رکتوم |
| عنوان لاتین مقاله | The effect of hemoglobin levels in rectal cancer survival |
| نوع ارائه | پوسترو سخنرانی |
| عنوان کنگره / همایش | بیست و دومین کنگره بیماری های گوارش و کبد ایران |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1401 |
| سال انتشار/ارائه میلادی | 2022 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1401/10/06 الی 1401/10/09 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://www.iaghcongress.org/ |
| آدرس علمی (Affiliation) نویسنده متقاضی | Liver and Gastrointestinal Disease Research Center, Tabriz University of medical sciences |
| نویسنده | نفر چندم مقاله |
|---|---|
| سید کاظم میری نژاد | اول |
| مصطفی اکبرزاده خیاوی | دوم |
| محمد حسین صومی | سوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | commonly severe in gastrointestinal tumors compared with anemia as a paraneoplastic phenomenon in other malignancies. The presence of anemia is related to aggressive tumor behavior and poor prognosis through exacerbating tumor hypoxia. Pretreatment anemia has shown significant prognostic value in solid cancers, including tumors of the rectum, stomach, esophagus, uterine cervix, and bladder. The aim of this study was to investigate the effect of hemoglobin levels on the survival rate of rectal cancer. Method: In this retrospective cohort study, 378 cases of RC were recorded from medical centers. Patients were divided into three groups based on hemoglobin levels, Anemia was Hb< 13 g/dL in men, and less than 12 g/dL in women. Severe anemia was Hb below 10 g/ dL. Data were analyzed using the Kaplan-Meier method and log-rank test for the univariate analysis of survival in various groups and p value < 0.05 was set as statistically significant. Result: Of the 378 patients analyzed, 223 (59 %) were males. The mean age was 57.7 ± 14.4, ranging from 15 to 86 years. The most common presenting was hematochezia (75.9%). The median Hb level was 12.50 g/dl, minimum 5.3 and maximum 19.9. The Pretreatment Hb value was inversely related to the pretreatment T stage of the tumor (P = 0.01). The median survival for mild anemia and severe anemia with local stage and highly stage were 50.33 Vs 27.7 and 26.4Vs 26.67 months respectively (p<0.05). The five-year survival rate among RC patients without anemia was 55%, compared to 39% for mild anemia and 32% for severe anemia (p<0.05) [Figure 1]. In conclusions- the pretreatment Hb level might be used as a biomarker of rectal tumor extension (T) and prognosis determination. |
| کلمات کلیدی | hemoglobin levels, rectal cancer, survival |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Mirinezhad.ICGH 2022-20.pdf | 1401/11/10 | 432437 | دانلود |
| certificate (2).pdf | 1401/11/10 | 136361 | دانلود |
