چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| فاطمه طباطبایی | اول |
| سیده طلا نبی پور حسینی | دوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Abstract Idiopathic thrombocytopenic purpura (ITP) or thrombocytopenic purpura is a hematological disease characterized by thrombocytopenia without a clear clinical etiology. It is an autoimmune disorder in which antibodies attach to the platelet plasma. This causes premature clearance of platelets by macrophages in the spleen as well as other reticular - endothelial system organs which may be acute or chronic. We want to introduce an 18-year-old woman G3P1D1Ab1 with sever thrombocytopenia at 18th weeks of gestational age with the diagnosis of refractory ITP complicating pregnancy. ITP can also occur in pregnancy. Other diseases with low platelet count such as preeclampsia and HELLP syndrome as well as thrombotic thrombocytopenic purpura (TTP) and acute fatty liver of pregnancy should be rule out before establish the diagnosis. The disease should be treated differently for pregnant women. Some patients do not require treatment. However, treatment is recommended in women with PLT count of less than 10000 or women with active bleeding. The first-line treatment includes corticosteroids plus anti-D antibody and IVIG. Further, 10-20% of patients are resistant to primary treatment with corticosteroids and IVIG or treatment with both. Splenectomy and immunosuppressive therapy and preterm pregnancy termination may be considered in such conditions. Key words ITP, Pregnancy, Splenectomy, Thrombocytopenia |
| کلمات کلیدی | Key words ITP, Pregnancy, Splenectomy, Thrombocytopenia |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 20221212_222139.jpg | 1401/09/21 | 3073328 | دانلود |
| ITP-pptx.pdf | 1401/09/21 | 908570 | دانلود |
| 2-Certificate.pdf | 1401/10/03 | 104293 | دانلود |
