| خلاصه مقاله | Introduction
The complexity of determining the presence and distribution of bone metastases is due to morphological, time-related, and location-related variations. Different imaging modalities have been used in this regard, with the benefits and shortcomings each. This study aims to assess the correlation of radionuclide bone scanning, magnetic resonance imaging (MRI), and computer tomography (CT) findings in the detection of bone metastases.
Materials and Methods
Of 152 patients with different types of cancers in Tabriz Imam Reza General Hospital, 46 patients with proven bone metastases by tissue biopsy were investigated in a cross-sectional study. Conformity and nonconformity between the findings obtained by radionuclide whole body bone scanning, MRI, and CT scanning with the presence or absence of bone metastases were investigated
Results
20 men and 26 women with a mean age of 61.02±12.63 (range 35-84) years were studied. Radioisotope scanning yielded positive results for bone metastases in 42 out of 46 patients (91.3%), MRI was positive in 37 out of 46 patients (80.4%), and CT scanning was positive in 30 out of 46 patients (65.2%). There was a significant concordance rate between radionuclide scan and MRI (kappa=0.35, p=0.003, concordance rate of 85.7%). However, there was no significant concordance between radionuclide scan and CT (kappa=0.20, p=0.06, concordance rate of 60.5%), as well as MRI and CT scan (kappa=0.44, p=0.05, concordance rate of 65%).
Conclusions
Our results provide strong evidence that there was significant concordance between the finding of radionuclide bone scan and MRI for diagnosis of bone metastasis. However, no significant concordance was found between radionuclide bone scan and CT as well as MRI and CT. |