| خلاصه مقاله | Platelet rich plasma ( obtained by centrifugation of whole blood is known as an autologous product that contains high concentrations of platelets in the plasma Autologous PRP gel due to the release of multiple growth factors and cytokines, including platelet derived growth factor ( vascular endothelial growth factor ( basal fibroblast growth factor ( transforming growth factor β (TGF β), and insulin like growth factor 1 (IGF 1 plays an important role in promoting tissue repair and regeneration In addition, PRP has shown promising experimental and clinical effects in wound healing, especially in chronic wounds, due to its low immunogenicity and high angiogenesis Several studies have been published on the evaluation of PRP gels in the process of healing various wounds As the field of surgery progresses, new therapies are needed to help treat more complex patients With countless musculoskeletal, gastrointestinal, and urological surgeries performed annually, surgical wound healing remains of paramount importance to the surgeon and patient Platelet concentrate has emerged as an adjunct therapy to help heal surgical wounds and injuries Therefore, we will discuss the restorative properties of platelet rich plasma in surgical wounds and its various applications in surgery |